Alzheimer disease (AD) is a progressive neurodegenerative brain disorder which plays an important role in neural cell destruction and as a result it causes memory loss in the patients. This disease is also the most common type of dementia which doesn’t completely respond to medical treatments so no certain cure is available. Recent studies show the advantages of using stem cells (SCs) in ...

introdouction: the purpose of the present study was to determine the possible relationship between gonial angle size and three mandibular morphometric parameters, namely, panoramic mandibular index (pmi), mandibular cortical width (mcw), and antegonial notch depth (ad), in digital panoramic radiographs. materials and methods: pmi, mcw, and ad were calculated in digital panoramic radiographs of ...

background and objective: alzheimer’s disease (ad) is a neurodegenerative disorder specified by deposition of b-amyloid (ab) and neuronal loss that leads to learning and memory disturbances. one of the most important causes of ad is glutamate-dependent excitotoxicity in brain regions that is vulnerable to ad. according to previous reported results, it was revealed that riluzole, as a glutamate ...

The most popular animal models of Alzheimer’s disease (AD) are transgenic mice expressing human genes with known mutations which do not represent the most abundant sporadic form of the disease. An increasing number of genetic, vascular and psychosocial data strongly support that the Octodon degus, a moderate-sized and diurnal precocial rodent, provides a naturalistic model for the study of the ...

alzheimers disease (ad) is by far the most common cause of dementia. definite diagnosis of ad is based on pathological findings. nincds-adrda criteria, published more than 25 years ago, are commonly used for the clinical diagnosis of ad. however, considering serious shortcomings of these criteria, new criteria have been proposed. according to these new criteria, ad can be diagnosed in predement...

Objective(s): Alzheimer’s disease (AD) is dysfunction of the central nervous system and as a neurodegenerative disease. The objective of this work is to investigate metabolic profiling in the serum of animal models of AD compared to healthy controls and then to peruse the role of ghrelin as a therapeutic approach for the AD.Materials and Methods: Nuclear magnetic resonance (NMR) technique was u...