Over-expression of AdeABC efflux pump stimulated continuously by the mutated AdeRS two component system has been found to result in antimicrobial resistance, even tigecycline (TGC) resistance, in multidrug-resistant Acinetobacter baumannii (MRAB). Although the insertion sequence, ISAba1, contributes to one of the AdeRS mutations, the detail mechanism remains unclear. In the present study we col...

Das Verständnis der Erdbebendynamik wird von hochauflösenden, gekoppelten Simulationen des Bruchprozesses und der seismischen Wellenausbreitung unterstützt. Für die benötigten hohen Auflösungen wird eine immense Menge an Höchstleistungsrechenressourcen verwendet, daher ist eine optimale Ausnutzung durch die Software unerlässlich. Getrieben durch aktuelle Entwicklungen in der Hardware erfordern ...

docrine systems, which have been considered as separate “systems” can be considered components of a single integrated defence mechanism in which the interactions between systems is as important to understanding adaptation as the interaction within a system (Ader, Cohen and Felten, 1995). The study of the response of this single integrated defense mechanism of the organism when it is exposed to ...

Systemic Lupus Eritematosus (SLE) is a systemic inflammatory disease often treated with the agent cyclophosphamide (CY), known by provoking important adverse reactions to the organism. Ader and Cohen have demonstrated an alternative way of administrating this agent based on pavlovian conditioning, in order to reduce the aggression caused by CY. Considering the influence of the temporal organiza...

. AIM: This study evaluates marginal sealing ability of currently available three self-etching adhesives in class V micro fill composite restorations. Materials and methods: Forty five human central incisors, divided in to three groups and class V cavities were prepared on the facial surface of teeth with occlusal margin in enamel and gingival margin in dentin/cementum. The cavities were restor...

BACKGROUND This study aimed to evaluate the role of efflux pump regulator and OXA-23 genes in imipenem resistance Acinetobacter baumannii strains isolated from hospitalized patients in Tehran, Iran. METHODS This study was conducted on 60 A. baumannii isolates collected from patients admitted to the Shahid Motahari and Taleghani Hospitals in Tehran during 2013-14. Antibiotic susceptibility tes...