Adverse drug reactions (ADRs) are considered among the leading causes of morbidity and mortality. Antidepressants, antipsychotics and mood stabilizers are associated with adverse effects which can affect the compliance and course of treatment in mental disorders. Clinicians' awareness about the adverse effects of psychotropic drugs and their preventability can foster rational and safe use of th...

Background: Adverse Drug Reactions (ADRs) underreporting is a serious drawback of the pharmacovigilance system. Spontaneous reporting of ADRs is a valid instrument to enhance pharmacovigilance. Objectives: To avoid prescribing again to patients the drug that caused them the ADRs, to evaluate spontaneous reporting of ADRs by patients to their General Practitioner (GP); to investigate the most in...

OBJECTIVE The purpose of this study was to investigate the incidence, cause, and influence of the adverse drug reactions (ADRs) associated with long-term intravenous antibiotics in patients with pyogenic spondylitis (PS). METHODS We retrospectively reviewed the medical records of 84 patients with PS who underwent intravenous antibiotic therapy in our hospital from January 2001 to December 201...

Contact me when new articles are published in these topic areas. A DVERSE DRUG AND DEVICE REactions (ADRs) account for as many as 100 000 deaths annually. 1 Prior to US Food and Drug Administration (FDA) approval, drugs are evaluated in well-designed and carefully monitored clinical trials. Only half of newly discovered serious ADRs are detected and documented in the Phy-sicians' Desk Reference...

user-generated medical messages on internet contain extensive information related to adverse drug reactions (adrs) and are known as valuable resources for post-marketing drug surveillance. the aim of this study was to find an effective method to identify messages related to adrs automatically from online user reviews.we conducted experiments on online user reviews using different feature set an...

Spontaneous adverse drug reactions (ADRs) reporting is a useful source of drug safety information in infants as only adult patients are routinely tested in clinical trials. This study was aimed to evaluate the spontaneously reported ADRs using WHO Adverse Reaction Terminology and to identify the common drugs associated with ADRs in children under 2 years of age. A retrospective analysis of ADR ...

Adverse drug reactions (ADRs) till date are still considered as one of the main problems therapy. Pharmacovigilance is monitoring safety by means spontaneous adverse-effect reporting systems, case control and cohort studies.
 This study evaluated levels awareness knowledge pharmacovigilance (i.e., ADR reporting) amongst final year students Rivers State College Health Science Technology, Po...

OBJECTIVES To prospectively determine the nature and rate of adverse drug reactions (ADRs) in children on antiepileptic drugs (AEDs) and to prospectively evaluate the effect of AEDs on behaviour. SETTING A single centre prospective observational study. PARTICIPANTS Children (<18 years old) receiving one or more AEDs for epilepsy, at each clinically determined follow-up visit. PRIMARY AND ...