BACKGROUND Early markers of diabetic autonomic neuropathy (DAN) in an electrocardiogram (ECG) include elevated R wave amplitudes, widening of QTc intervals and decreased heart rate variability (HRV). The severity of DAN has a direct relationship with mortality risk. Aerobic exercise training is a common recommendation for the delay and possible reversal of cardiac dysfunction. Limited research ...

This meta-analysis of controlled clinical trials quantifies the effect of aerobic exercise on VO2max (aerobic fitness) among sedentary older adults and examines the associations of such magnitude with variables of intervention. Forty-one trials including 2102 older subjects (within-group mean age of 60 years and older) were identified by searches of databases, hand searching, and cross-referenc...

Background and Objective: The purpose of this study was to investigate the preconditioning effect of aerobic exercise with vitamin D3 consumption on vascular endothelial growth factor (VEGF) level in the 6-hydroxydopamine (6-OHDA)-lesioned rat model of Parkinson’s disease. Materials and Methods: Forty-eight male rats weighing 250-300 g were randomly assigned to 6 groups: healthy control, Parkin...

This paper describes aerobic digester design for the biodegradation of plant tannins in industrial wastewater. For optimal design, using the criterion of minimal total holding time, some experimental investigations into tannins’ biodegradation rate in industrial wastewater were performed in the first part of this research. The chemical oxygen demand method (COD) was applied to follow the tannin...

retinol binding protein4 (rbp4) such as adipocytokines that could be a marker for type 2 diabetes and seems to be leading to increased insulin resistance. the purpose of this study was to evaluate the effect of aerobic training on serum rbp4 and insulin resistance in adult male rats. in the present experimental study 16 wistar rats were randomly divided to one of the exercise group (n=10) or co...

Cells in homeostasis metabolize glucose mainly through the tricarboxylic acid cycle and oxidative phosphorylation, while activated cells switch their basal metabolism to aerobic glycolysis. In this study, we examined whether metabolic reprogramming toward aerobic glycolysis is important for the host response to Mycobacterium tuberculosis (Mtb). Through transcriptional and metabolite analysis we...

To test hypotheses concerning physiological factors limiting the rate of aerobic exercise metabolism, we used a unique experimental evolution model: lines of bank voles selected for high swim-induced aerobic metabolism (A) and unselected, control lines (C). We investigated putative adaptations that result in the increased performance of the hindlimb muscle (gastrocnemius joined with plantaris)....

......................................................................................................................................... v Introduction ................................................................................................................................... 1 Saccharomyces cerevisiae as a model system ......................................................................