One of the determinant factors for successful bioengineering is to achieve appropriate nano-topography and three-dimensional substrate. In this research, polycaprolactone (PCL) nano-fibrous mat with different roughness modified with O2 plasma was fabricated via electrospinning. The purpose of this study was to evaluate the effect of plasma modification along with surface nano-topography of mats...

Measurement of force on a micro- or nano-Newton scale is important when exploring the mechanical properties of materials in the biophysics and nanomechanical fields. The atomic force microscope (AFM) is widely used in microforce measurement. The cantilever probe works as an AFM force sensor, and the spring constant of the cantilever is of great significance to the accuracy of the measurement re...

BACKGROUND Ionotropic glutamate receptors (iGluRs) are responsible for extracellular signaling in the central nervous system. However, the relationship between the overall structure of the protein and its function has yet to be resolved. Atomic force microscopy (AFM) is an important technique that allows nano-scale imaging in liquid. In the present work we have succeeded in imaging by AFM of th...

In this paper, the effect of air relative humidity and capillary force on contact geometry of surfaces based on JKR model by Atomic force microscopy was investigated in order to manipulate nano-particles. With transition from macro to nano-scale, the effect of surface forces becomes more significant in comparison with inertial force. Because contact mechanics models are based on surface energy ...

The corrosion resistant coatings used conventionally are susceptible to degradation, leading to pitting corrosion. This report summarizes the corrosion resistant nature of thin films of Cu-TiO2 coated on mild steel, in different corrosion environments. Nano meter thick (100nm, 125nm, 150nm) composite coatings were coated on steel substrate by RF magnetron sputtering technique. The required targ...

As an inhibitor of microtubule assembly, combretastatin A-4 (CA-4)-induced biological responses in tumor cells have been well known, but the corresponding changes in nano-biophysical properties were not investigated given the lack of an ideal tool. Using AFM technique, we investigated the alteration of nano-biophysical properties when CA-4-treated tumor cells underwent the different biological ...

Understanding the relationships between viral material properties (stiffness, strength, charge density, adhesion, hydration, viscosity, etc.), structure (protein sub-units, genome, surface receptors, appendages), and functions (self-assembly, stability, disassembly, infection) is of significant importance in physical virology and nanomedicine. Conventional Atomic Force Microscopy (AFM) methods ...

Electron beam lithography (EBL) has become a popular means to prepare a wide variety of nano-arrays for numerous studies and applications, including photonics and sensors. Their fabrications and characterizations are costly and time consuming, underscoring the importance of developing effective tools to rapidly study their physicochemical stabilities and properties over time. In this study, we ...

Monocyte-chemoattractant protein-1 (MCP-1), also known as CCL2, is a potent chemoattractant of T cells and monocytes, involved in inflammatory and angio-proliferative brain and retinal diseases. Higher expression of MCP-1 is observed in metastatic tumors. Unusual levels of MCP-1 in the brain may be correlated with autism. Immunochemistry where atomic force microscope (AFM) tips functionalized w...

Using C2H2, 112 and As gases at 550'C, carbon nanotubes were fabricated on the surfaces of twosubstrates coated by nano thin layers of metal catalysts by DC magnetron sputtering. AYStamless steel andFe/CteAl, by thermal chemical vapor deposition (TCVD) The surface properties of the substrates wereparticularly investigated, and the effect of treatment of the substrates on the CNT's growth is cri...