The mAgNOR and pAgNOR counts reflecting the number of rDNA genes being transcribed, showed a highly significant increase from control values following administration of 5X, 10X, 15X doses of enrofloxacin in chicken. The maximum increase for both, mAgNOR and pAgNOR was shown by birds receiving 15X dose, sacrificed 48 hr after the last drug injection. The increase of pAgNOR at 5X (24 hr) was not ...

The variations in the numbers of nucleolar organising regions (NORs) among different grades of cervical intraepithelial neoplasia (CIN) were investigated using a silver staining technique. Twenty four biopsy specimens were studied (six normal and six of each of the three grades of CIN) by staining paraffin wax sections using a silver (AgNOR) method that stains the NORS as multiple black dots wi...

The study sought a correlation between the number of AgNOR granules and the degree of cervical intraepithelial neoplasia (CIN). Thirty-five sections (5 normal, 10 CIN1, 10 CIN2 and 10 CIN3) were subjected to retrospective analysis. The percentage of cells with 1, 2, 3, 4 and more AgNORs was calculated and the number of granules per 100 cells was counted. The number of cells containing single gr...

Background: The health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. Objective: The purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (AgNOR) staining. Methods: Oral smears were collected from clinically normal-appearing buccal mucosa b...

Objectives The aim of this study is finding a practical and easy way to differentiate, between two malignant tumors Adenoid Cystic Carcinoma (ACC) and Polymorphous Low-grade Adeno Carcinoma (PLGA) histologically. In this regard, We proposed silver nitrate staining (AgNOR). Methods In this cross-sectional study, 30 parrafin-embedded blocks of ACC and 9 paraffin-embedded b...

Prof. Dr. K. Metze, Department of Pathology, Faculty of Medicine, POB 6111, State University of Campinas, BR 13081 Campinas-SP (Brazil) Nucleolar organizer regions (AgNORs) have been widely studied in a variety of neoplasias, but only a few investigations deal with AgNORs in blood diseases. We therefore read with interest the study by Nakamura et al. [1] on AgNORs in acute leuke-mias, and would...