نتایج جستجو برای: alarmins

تعداد نتایج: 2072  

2008
Ying Xu Manesh Shah Sherri Matis Xiaojun Guan Edward C. Uberbacher

Journal: :Science 2012
Weldy V Bonilla Anja Fröhlich Karin Senn Sandra Kallert Marylise Fernandez Susan Johnson Mario Kreutzfeldt Ahmed N Hegazy Christina Schrick Padraic G Fallon Roman Klemenz Susumu Nakae Heiko Adler Doron Merkler Max Löhning Daniel D Pinschewer

Pathogen-associated molecular patterns decisively influence antiviral immune responses, whereas the contribution of endogenous signals of tissue damage, also known as damage-associated molecular patterns or alarmins, remains ill defined. We show that interleukin-33 (IL-33), an alarmin released from necrotic cells, is necessary for potent CD8(+) T cell (CTL) responses to replicating, prototypic ...

Journal: :Contact dermatitis 2017
Sjors A Koppes Kristiane A Engebretsen Tove Agner Irena Angelova-Fischer Teresa Berents Johanna Brandner Richard Brans Maja-Lisa Clausen Edith Hummler Ivone Jakasa Ružica Jurakić-Tončic Swen M John Denis Khnykin Sonja Molin Jan O Holm Sari Suomela Hermann-Josef Thierse Sanja Kezic Stefan F Martin Jacob P Thyssen

Contact sensitization is common and affects up to 20% of the general population. The clinical manifestation of contact sensitization is allergic contact dermatitis. This is a clinical expression that is sometimes difficult to distinguish from other types of dermatitis, for example irritant and atopic dermatitis. Several studies have examined the pathogenesis and severity of allergic contact der...

2012
Stefanie Hirsiger Hans-Peter Simmen Clément M. L. Werner Guido A. Wanner Daniel Rittirsch

Sterile injury can cause a systemic inflammatory response syndrome (SIRS) that resembles the host response during sepsis. The inflammatory response following trauma comprises various systems of the human body which are cross-linked with each other within a highly complex network of inflammation. Endogenous danger signals (danger-associated molecular patterns; DAMPs; alarmins) as well as exogeno...

Journal: :Journal of clinical and experimental hematopathology : JCEH 2011
Michiaki Takagi

Toll like receptor (TLR), one of the key functions of innate immune system, can recognize not only exogenous pathogen-associated molecular patterns, namely PAMPs, but also endogenous molecules created upon tissue injury, sterile inflammation and degeneration. Endogenous TLR ligands are called as damage-associated molecular patters (DAMPs), including endogenous molecules released by activated an...

2015
Benjamin Schwessinger Ofir Bahar Nicholas Thomas Nicolas Holton Vladimir Nekrasov Deling Ruan Patrick E. Canlas Arsalan Daudi Christopher J. Petzold Vasanth R. Singan Rita Kuo Mansi Chovatia Christopher Daum Joshua L. Heazlewood Cyril Zipfel Pamela C. Ronald

[This corrects the article DOI: 10.1371/journal.ppat.1004809.].

2010
David H. Foster DAVID H. FOSTER

The capacity of the visual system to recognize patterns that have undergone various transformations may be explained by a scheme in which the system associates with each pattern certain features and feature-relations that remain constant under the action of the given transformations . Some of the characteristics of such a recognition scheme are examined and an approach is proposed for the analy...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید