Acetone extract of Stem of Ocimum gratissimum was screened for the antifertility activity in proven fertile female albino rats at the doses 100, 200 and 500 mg/kg b.wt./day. Oral administration of the extract to mated female rats on days 1-5 of pregnancy resulted in a decline in the fertility index, numbers of uterine implants and live fetuses in a dose dependent manner as was confirmed by lapa...

The present work was designed to test the toxic impacts exerted by the colour additives erythrosine on the histology, ultrastructure and some serum liver function parameters in male albino rats. Erythrosine in a dose level equals 136 mg/kg bw was given orally to male albino rats for 4, 6 and 8 weeks. This caused time-dependent histological alterations in liver such as cytoplasmic vacuolization ...

Mancozeb, an Inorganic-zinc dithiocarbamate is a typical fungicide with carbamate structure. It is chemically identified as ethylenebisdithiocarbamate (EBDC). It is commonly used for foliar application and seed treatment in agriculture. The present work was conducted to assess the protective effect of vitamin C against Mancozeb induced toxicity in the Testicular activity of adult albino rats. 9...

Metronidazole is an antibiotic which is widely used in the treatment of parasitic diseases. Several studies have reported its tumorigenic, mutagenic and antimicrobial effects, but there is a dearth of information on its effect on blood chemistry. This study was designed to investigate its effect on haematological parameters in male albino rats. Treatment of rats for 25 days with 400 mg/kg BW of...

Effect of spirulina and Liv-52 on lead induced hypercholesteroleamia in albino rats was studied. Oral administration of lead acetate(10mg/kg body weight/day) for 30 days resulted in a significant increase(P<0.01) in the level of serum total cholesterol, triglycerides, LDL Cholesterol and a significant decreases in the level of serum HDL cholesterol, when compared to normal and control group of ...

This study aimed to attain a comparison in pharmacokinetic parameters of ondansetron after transdermal (as invasomes gel) and oral solution) routes. Ondansetron is 5 ? hydroxytryptamine receptor antagonist used for chemotherapy radiotherapy induced nausea emesis. The was performed using Wistar albino rats weighing 200 &plusmn;20 g divided into two groups (6 each). A dose 0.28 mg ondansetron, eq...

The effects of oral administration of Hibiscus sabdariffa aqueous extract on some haematological parameters of wistar albino rats were studied. A total of twenty five (25) male albino rats were grouped randomly into groups. Group A (control), Group B (0.6g/100ml of water of HS extract) Group C (1.2g/100ml HS extract), Group D (1.8g/100ml HS extract) and Group E (1.8g/100ml + vitamin C) and trea...

background and objectives rheumatoid arthritis (ra) is a chronic inflammatory disease which is characterized by joint swelling, and synovial inflammation. c reactive protein (crp) and ceruloplasmin (cp) are identified as important biomarkers of ra and various inflammatory diseases. curcumin, a widely used yellow color spice is the most active component of curcuma longa l (turmeric). curcumin co...

BACKGROUND Hypercholesterolemia is a condition characterised with high level of cholesterol in the blood. OBJECTIVES The effect of ethanolic extract of Buchholzia coriacea (EEBC) on the lipid profile levels and extent of lipid peroxidation in hypercholesterolemic albino rats was investigated in this study. METHODS Thirty albino rats were divided into six different groups which consist of gr...

The anti-fertility activity of prostaglandin synthesis inhibitors namely the non-steroidal anti-inflammatory drugs: acetyl salicylic acid, indomethacin and oxyphenbutazone were investigated in male and female albino rats and female albino rabbits. Oxyphenbutazone and indomethacin affected the reproductive process in male rats. Indomethacin 3 mg/kg. and acetyl salicylic acid 300 mg/kg produced s...