The average lifespan of artificial joints is 15–25 years, but it still too short for young and active patients. Human synovial albumin easily adsorbed on the surfaces joint materials has increased friction when subjected to conformational changes. Most studies have focused interaction between fluid components protein conformation not been modified, how reduce wear caused by denatured proteins. ...

Human serum albumin (HSA) is a complex protein with multiple functions and plays a key role in organ system homeostasis. Changes in albumin levels are associated with worsened outcome in critical illness. However, serum albumin functional activities cannot be easily determined to assess its capacities in illness. Two real-time and sensitive fluorescent liposome assays were developed to determin...

The serum of a patient (L'ec) with an IgM lambda monoclonal protein was noted to bind albumin on immunoelectrophoresis. Analytical ultracentrifugation of the L'ec serum demonstrated 23S and 12S peaks, but no 4S (albumin) boundary. Immunologically identical 20S and 9S IgM proteins were isolated from the serum and the addition in vitro of either the patient's albumin or albumin isolated from norm...

High-protein diets increase albumin synthesis in rats with Heymann nephritis but albuminuria increases also, causing serum albumin concentration to be suppressed further than in nephrotic animals eating a low-protein diet. Experiments were designed to determine whether dietary protein augmentation directly stimulates albumin synthesis, or whether instead increased albumin synthesis is triggered...

BACKGROUND Controversy exists regarding occurrence and measurement of structural variants of albumin in urine. In this study, we examined cross-reactivity of in vitro modified albumins in assays for urine albumin (microalbumin). METHODS We analyzed albumin modified by reagents, trypsin, or physical treatments or differing in primary sequence (animal albumins) with an immunoturbidimetric assay...

evaluation of serum albumin level and its effect on prognosis in patients admitted to intensive care unit    valizadeh hasanloei ma [1] , norozinia h [2] *, shateri k [3] , bakhtyari l [4] , hosseinpour h [5]     received: 18 sep , 2013 accepted: 21 nov , 2013   abstract   background & aims : albumin and globulin are the largest components of the body proteins. albumin is a protein made in the ...

To determine whether equilibrium binding between albumin and hepatocytes involves a cell surface receptor for albumin, we incubated freshly isolated rat hepatocytes with 125I-albumin and determined the amount of albumin associated with the cells as a function of the total albumin concentration. The resulting two-phase binding curve showed the rat albumin-hepatocyte interaction to consist of a s...