The aim of this study was to determine whether moderate restriction of dietary salt intake leads to an additional fall in blood pressure in treated hypertensive men who are asked to simultaneously reduce their usual alcohol intake. Sixty-three subjects entered an initial 2-week familiarization period during which they continued their usual alcohol intake and commenced a "low sodium" diet (less ...

The interoceptive effects of alcohol are major determinants of addiction liability. Metabotropic glutamate (mGlu) receptors are widely expressed in striatal circuits known to modulate drug-seeking. Given that the interoceptive effects of drugs can be important determinants of abuse liability, we hypothesized that striatal mGlu receptors modulate the interoceptive effects of alcohol. Using drug ...

BACKGROUND Currently available gene delivery vehicles have many limitations such as low gene delivery efficiency and high cytotoxicity. To overcome these drawbacks, we designed and synthesized two cationic lipids comprised of n-tetradecyl alcohol as the hydrophobic moiety, 3-hydrocarbon chain as the spacer, and different counterions (eg, hydrogen chloride [HCl] salt or trifluoroacetic acid [TFA...

addiction to drugs, such as heroin, cocaine and alcohol, exacts great human and financial costs on society. various evidence-based pharmacological and psychosocial interventions are currently used in the treatment of drug addiction but they do not produce adequate therapeutic benefits in every patient. further, barriers such as financial cost, lack of availability, or perceptions of existing tr...

conclusions based on our findings, it is crucial to implement well-designed educational programs to improve hypertension self-care behaviors. background an assessment of an individual’s hypertension self-care behavior may provide clinicians and practitioners with important information regarding how to better control hypertension. objectives the objective of this study was to investigate the sel...

The increasing prevalence of hypertension in adolescents is a growing public health problem. This study aimed to determine the risk factors for adolescents. A literature review was conducted and 20 relevant articles were found by searching Pubmed (n = 7), Proquest 6), Science Direct 3), Google Scholar 4). data search keywords “risk factor AND OR teenager juvenile”. According results, include hi...

The recent interest in health promotion and disease prevention has drawn attention to the role of the alcohol and junk-food industries. Companies supplying, producing, advertising or selling alcohol or junk food (ie, foods with a high content of fat, sugar or salt) do so to generate profits. Even companies marketing "low-carbohydrate" beers, "mild" cigarettes, or "high-fibre" sugary cereals are...

In order to enable exploitation of noble metal/poly(vinyl-alcohol) nanocomposites for device fabrication, solutions of poly(vinyl-alcohol) suitable for piezo-driven inkjet printing techniques are identified and discussed in terms of their material properties. The printable poly(vinyl-alcohol) medium is then exploited as a host material through the formation of silver or gold nanoparticles in or...

Semi-interpenetrating polymer network (semi-IPN) technology was introduced in order to improve the gel strength and salt resistance of itaconic acid (IA)-based superabsorbent polymers (SAPs). A semi-IPN SAP based on IA 2-acrylamido-2-methyl-1-propanesulfonic (AMPS) synthesized. Polymerization performed using a one-pot method an aqueous solution presence polyvinyl alcohol (PVA). The structural t...

The American comedian Henny Youngman (1906–1998) once said, ‘When I read about the evils of drinking, I gave up reading.’ Ironic, but interestingly as though with a sense of foresight, he did not speak of giving up drinking! It is despite the fact that alcohol is responsible for increased illness, being causally related to more than 60 different medical conditions (Rehm et al., 2003). Around 4%...