in the present study, we examined the relationship between family history of cardiovascular diseases (cvd), dyslipidemia, hypertension, and diabetes with laboratorial abnormalities and syndromes in iranian patients with non-alcoholic fatty liver disease (nafld). a total of 332 nafld patients from our outpatient clinic were consecutively entered into analysis. exclusion criteria were having diab...

background: a hypothesis has been presented about the role of serum iron, ferritin and transferrin saturation among patients with non-alcoholic fatty liver disease (nafld) and resistance to insulin (metabolic syndrome [mets]), but there is much controversy. this study aimed at investigating the level of serum iron and demographic characteristics in patients with nafld with or without mets. meth...

abstract background: vitamin d supplementation has been shown to decrease insulin resistance through which it might cause fatty liver. fatty liver increasingly results in type 2 diabetes mellitus (t2dm). insulin resistance and fatty liver are particularly closely related. the aim of present study is to examine the effect of vitamin d supplementation on blood sugar and different indices of insul...

Alcoholic liver disease (ALD) is a global liver disease which characterized by liver inflammation, fatty liver, alcoholic hepatitis, or liver cirrhosis. Alcohol abuse is one of the main reasons for liver disease. Alcoholic fatty liver (AFL) disease is the early stage of ALD and associated with the excessive lipids accumulation in hepatocytes as well as oxidative stress. MicroRNA-203 (miR-203) i...

BACKGROUND Chronic oxidative stress is one of the key mechanisms responsible for disease progression in non-alcoholic fatty liver disease. However, so far, few studies reported increased circulating levels of oxidative stress markers in patients with non-alcoholic fatty liver and no study has been performed with newer markers of systemic oxidative stress. The aim was to assess the relationship ...

BACKGROUND AND AIM Data on quantitative metabolic liver functions in the life-threatening disease alcoholic hepatitis are scarce. Urea synthesis is an essential metabolic liver function that plays a key regulatory role in nitrogen homeostasis. The urea synthesis capacity decreases in patients with compromised liver function, whereas it increases in patients with inflammation. Alcoholic hepatiti...

Using an indirect immunofluorescence technique liver membrane antibodies of IgG and IgA class have been demonstrated in a statistically significant proportion of sera from patients with alcoholic hepatitis and alcoholic cirrhosis. IgG and IgA class antibodies were found respectively in 23 and 25% of 48 patients with alcoholic hepatitis, in 27 and 33% of 84 with active cirrhosis, and 67 and 58% ...