1 Università degli Studi “Aldo Moro” di Bari, Dip. Chimica, Via Orabona, 4, 70126 Bari, Italy; [email protected] (V.R.); [email protected] (F.D.A.); [email protected] (A.A.); [email protected] (P.S.) 2 Università degli Studi “Aldo Moro” di Bari, Dip. di Farmacia-Scienze del Farmaco, via orabona 4, 70126 Bari, Italy; [email protected] 3 Consiglio Nazionale delle Ricer...

Previous studies have reported an exaggerated natriuresis in hypertensive man; however, a systematic appraisal of this response in various forms of hypertension has not been made. We measured fractional excretion of sodium (FENa) during a four hour intravenous infusion of 2 liters normal saline in 162 normal subjects and 120 hypertensives. Of these, 13 had primary aldosteronism (ALDO), 19 high ...