Contact-allergic reactions to cosmetics may be delayed-type reactions such as allergic and photo-allergic contact dermatitis, and more exceptionally also immediate-type reactions, that is, contact urticaria. Fragrances and preservative agents are the most important contact allergens, but reactions also occur to category-specific products such as hair dyes and other hair-care products, nail cosm...

PURPOSE Amide type local anesthetic agents are among the most commonly used drugs in medicine. Several adverse drug reactions (ADRs) have been previously described with their use. Among them, allergic reactions are considered rare. The aim of this study was to describe the main characteristics of ADRs induced by amide type local anesthetic drugs. METHODS We studied reports recorded in the Fre...

BACKGROUND In peanut and tree nut allergic children a history of anaphylaxis is associated with subsequent severe reactions. OBJECTIVE We aimed to prospectively rechallenge peanut and tree nut allergic children with a history of mild/moderate reactions to assess their allergy over time. METHODS In this cohort study peanut and tree nut allergic children with a history of mild/moderate reacti...

Proton pump inhibitors (PPIs) are widely prescribed drugs in daily practice. Allergic reactions, even small number of anaphylactic reactions to PPIs have been reported. Omeprazole, lansoprazole, pantoprazole, rapeprazol and esomeprazole are classified in the same group. Despite the similarity of biochemical structures among these drugs, presence of cross-reactivity between PPIs is controversial...

© 2015 The Authors. doi: 10.2340/00015555Journal Compilation © 2015 Acta Dermato-Venereologica. ISSN 0001-5555 Sulphites, such as sodium bisulphite and sodium metabisulphite, are widely used as antioxidants or preservatives in a wide range of substances, such as food, cosmetics and medications (1). It has been reported that sulphite intake can cause systemic type I allergic reactions, such as u...

BACKGROUND Food allergy can cause life threatening reactions. Currently, patients with severe food allergy are advised to avoid foods which provoke allergic reactions. This has become increasingly difficult as food proteins are being added to a broader range of consumer products. PATIENTS AND METHODS Here we describe our investigations into the allergenicity of a new drink when two cow's milk...

Most anticancer treatments carry a risk for infusion reactions (IRs); incidence may increase when different agents are administered concomitantly. IRs are either allergic reactions to foreign proteins [generally immunoglobulin E (IgE)-mediated allergic responses] or non-immune-mediated reactions [1]. Most IRs are mild with symptoms such as chills, fever, nausea, headache, skin rash, pruritus, e...

S INCE September, 1977, the Pennsylvania statewide hemophilia centers have recorded data concerning immediate reactions occurring after administration ofcommercial factor VIII and factor IX concentrates. This communication reports the frequencies and types of the immediate reactions caused by these concentrates. Generally, there were two broad types of immediate reactions (Table 1 ): allergic a...