In this paper, we are concerned with the fractional and higher order H\'{e}non-Hardy type equations \begin{equation*} (-\Delta)^{\frac{\alpha}{2}}u(x)=f(x,u(x)) \,\,\,\,\,\,\,\,\,\,\,\, \text{in} \,\,\, \mathbb{R}^{n}, \mathbb{R}^{n}_{+} \text{or} \Omega \end{equation*} $n>\alpha$, $0<\alpha<2$ or $\alpha=2m$ $1\leq m<\frac{n}{2}$. We first consider typical case $f(x,u)=|x|^{a}u^{p}$ $a\in(-\al...