نتایج جستجو برای: alpha interleukins child heart defects

تعداد نتایج: 861547  

Journal: :British heart journal 1977
G D Oakley P H Carson J M Sanderson

A patient with alpha-haemolytic streptococcus endocarditis on a ventricular septal defect is described. The disease spread to involve both tricuspid and pulmonary valves which were largely destroyed. The patient developed severe right heart failure with pronounced rise in right atrial pressure. This led to right-to-left shunting through the foramen ovale with systemic embolization. She was succ...

ژورنال: طب کار 2017

Introduction: Recognition of maternal exposure to solvents and its relationship with congenital heart defects in infants can be effective in identifying effective environmental factors in the occurrence of anomalies. The aim of this study was to determine the relationship between maternal occupational exposure to solvent and birth congenital heart defects in infants. Method: In this case contr...

Journal: :Journal of autism and developmental disorders 2012
Ioanna Tsiouri Elizabeth Schoen Simmons Rhea Paul

This study evaluates the effectiveness of an intervention package including a discrete trial program (Rapid Motor Imitation Antecedent Training (Tsiouri and Greer, J Behav Educat 12:185-206, 2003) combined with parent education for eliciting first words in children with ASD who had little or no spoken language. Evaluation of the approach includes specific intervention targets and functional spo...

Journal: :Development 1992
K Morrison-Graham G C Schatteman T Bork D F Bowen-Pope J A Weston

The Patch (Ph) mutation in mice is a deletion of the gene encoding the platelet-derived growth factor receptor alpha subunit (PDGFR alpha). Patch is a recessive lethal recognized in heterozygotes by its effect on the pattern of neural crest-derived pigment cells, and in homozygous mutant embryos by visible defects in craniofacial structures. Since both pigment cells and craniofacial structures ...

Journal: :Genome Biology 2003

Journal: :the journal of tehran university heart center 0
hamzullah khan department of cardiology, postgraduate medical institute, lady reading hospital, peshawar, pakistan. hikmatullah jan department of cardiology, postgraduate medical institute, lady reading hospital, peshawar, pakistan. muhammad hafizullah department of cardiology, postgraduate medical institute, lady reading hospital, peshawar, pakistan.

background: we sought to determine the frequency of the risk factors for congestive cardiac failure (ccf) in a tertiary care hospital in peshawar, pakistan. methods: this retrospective, observational study was conducted in the department of cardiology, postgraduate medical institute, lady reading hospital peshawar, from march 2005 to september 2007. relevant information regarding the risk facto...

Journal: :Circulation 2005
Ara Parlakian Claude Charvet Brigitte Escoubet Mathias Mericskay Jeffery D Molkentin Guillaume Gary-Bobo Leon J De Windt Marie-Aline Ludosky Denise Paulin Dominique Daegelen David Tuil Zhenlin Li

BACKGROUND Serum response factor (SRF) is a cardiac transcription factor involved in cell growth and differentiation. We have shown, using the Cre/loxP system, that cardiac-specific disruption of SRF gene in the embryonic heart results in lethal cardiac defects. The role of SRF in adult heart is unknown. METHODS AND RESULTS We disrupted SRF in the adult heart using a heart-specific tamoxifen-...

2015
Mohammad Mehdi Akhondi

The Parliament of Great Britain approved three-parent IVF project with 382 votes for and 128 votes against it on 3rd February, 2015. In case of the project approval in House of Lords, Great Britain would be the first country which legalizes the action. The purpose of this procedure is prevention of genetic diseases with mitochondrial defects in which the defective mitochondria in the cytoplasm ...

Journal: :Circulation. Cardiovascular genetics 2013
Nicole Corsten-Janssen Wilhelmina S Kerstjens-Frederikse Gideon J du Marchie Sarvaas Maria E Baardman Marian K Bakker Jorieke E H Bergman Hanne D Hove Ketil R Heimdal Cecilie F Rustad Raoul C M Hennekam Robert M W Hofstra Lies H Hoefsloot Conny M A Van Ravenswaaij-Arts Livia Kapusta

BACKGROUND Loss-of-function mutations in CHD7 cause Coloboma, Heart Disease, Atresia of Choanae, Retardation of Growth and/or Development, Genital Hypoplasia, and Ear Abnormalities With or Without Deafness (CHARGE) syndrome, a variable combination of multiple congenital malformations including heart defects. Heart defects are reported in 70% to 92% of patients with a CHD7 mutation, but most stu...

2016
Udit Agarwal Amanda W. Smith Kristin M. French Archana V. Boopathy Alex George David Trac Milton E. Brown Ming Shen Rong Jiang Janet D. Fernandez Brian E. Kogon Kirk R. Kanter Baahaldin Alsoufi Mary B. Wagner Manu O. Platt Michael E. Davis

UNLABELLED Children with congenital heart diseases have increased morbidity and mortality, despite various surgical treatments, therefore warranting better treatment strategies. Here we investigate the role of age of human pediatric cardiac progenitor cells (hCPCs) on ventricular remodeling in a model of juvenile heart failure. hCPCs isolated from children undergoing reconstructive surgeries we...

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