Alternative splicing is a major contributor to genomic complexity, disease, and development. Previous studies have captured some of the characteristics that distinguish alternative splicing from constitutive splicing. However, most published work only focuses on skipped exons and/or a single species. Here we take advantage of the highly curated data in the MAASE database (see related paper in t...

One year after the discovery of exons and introns in the adenoviral hexon gene by the teams of Roberts and Sharp [1,2], Walther Gilbert suggested that the employment of different exons of a single gene could lead to the generation of various mRNA isoforms [3], a process that is today known as alternative splicing. Alternative splicing implies a number of distinct mechanisms including exon skipp...

Multi-storey buildings require mitigation of consequences unexpected or accidental events, to prevent disproportionate collapse after an initial damage. Cross-laminated timber (CLT) in platform-type construction is increasingly used for multi-storey buildings, however, the behaviour and alternative load paths (ALPs) are not fully understood. A 3D non-linear component-based finite element model ...

Corporate social responsibility (CSR) emerged to deliver sustainable economic, environmental, and value organization's extended stakeholders society in general. This study investigates the similarities, differences, relationships between B Corp, ISO 9001, 14001 certifications is supported by a mixed research methodology sample of 701 Corp companies certified January 2020 March 2021. The results...

Can one make a Majorana field theory for fermions starting from the zero mass Weyl theory, then adding a mass term as an interaction? The answer to this question is: yes we can. We can proceed similarly to the case of the Dirac massive field theory[1]. In both cases one can start from the zero mass Weyl theory and then add a mass term as an interacting term of massless particles with a constant...