INTRODUCTION Cockroach allergen exposure elicits cockroach sensitization and poses an increased risk for asthma. However, the major components in cockroach allergen and the mechanisms underlying the induction of cockroach allergen-induced allergy and asthma remain largely elusive. We sought to examine the role of cockroach-associated glycan in regulating human basophil function. METHODS N-lin...

PURPOSE Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there is limited information on IgE epitopes and tissue localization of Per a 2. This study aimed to identify Per a 2 linear IgE-binding epitopes and its distribution in the body of a cockroach. ...

the susceptibility of 5 wild strains of german cockroach collected from five infected flats in tehran were assessed by tests of surface contact method to cyfluthrin, permethrin, sumithrin and lambdacyhalothrin. comparison of the result of knockdown tests on the wild strains with a standard susceptible strain indicated that all the strains are resistant to sumithrin, i.e., resistance ratio, the ...

In dim light, reliable coding of visual information becomes compromised, unless the sensitivity of the visual system to light is improved by structural and functional adaptations. Thus far, many adaptations for night vision in the compound eyes of nocturnal insects have been described, but little is known about the mechanisms underlying the electrochemical signalling in their photoreceptors. In...

An imidacloprid-related nitromethylene compound and its alkyl congeners at the imidazolidine NH site were prepared and their insecticidal and nerve-excitatory and -blocking activities were measured. In the insecticidal test with the male adult American cockroach by the injection method, metabolic inhibitors, more or less, increased the activity of tested compounds. The NH mother compound was th...

Asthma is a major public health concern. Cockroach allergen exposure and cockroach allergic sensitization could contribute to the higher prevalence of asthma. However, the underlying immune mechanism and the genetic etiology remain unclear. Recent advances have demonstrated that several receptors (PAR-2, TLRs, CLRs) and their pathways mediate antigen uptake from the environment and induce aller...

BACKGROUND Cockroach allergy is common among inner city children with asthma, and exposure to cockroach allergen is associated with more severe disease. However, there has been little evaluation of educational approaches for controlling cockroach infestations and reducing allergen exposure. OBJECTIVE An educational intervention to reduce cockroach allergen exposure in the homes of Hispanic ch...