Abstract Background Fungal stem end rot disease of pitaya caused by Alternaria alternata is one the most destructive diseases in Binh Thuan province, Vietnam. This study aimed to assess antagonistic effects some endophytic bacteria isolated from weed plant ( Echinochloa colonum ) against A. . Results A total 19 were and 5 them presented vitro activity alternata. Of five, strain EC80 significant...

Background: Thymus persicus is one of the Iranian endemic medicinal plants, that its decoction and various products have plenty of food and pharmaceutical uses. Objective: Evaluation of T. persicus products metabolite contains and determination of the best antioxidant, anti-diabetic and anti-Alzheimer extract. Methods: Samples total phenolic, flavonoid and tannin contents were determined by F...

The inhibition of enzymes involved in the breakdown of carbohydrates is considered a therapeutic approach to the management of type-2 diabetes. This study sought to investigate the effects of essential oil from clove bud on α-amylase and α-glucosidase activities. Essential oil from clove bud was extracted by hydrodistillation, dried with anhydrous Na2SO4 and characterized using gas chromatograp...

The α-amylase inhibition and binding behaviors of shikimic acid its structural analogues were studied. Uncompetitive characteristic was identified through several linear transformation equations enzymatic data considering the good linearity. Interestingly, change in concentrations starch would not decrease inhibitory effects with various used present study. effect reduced greatly after ethyl es...

We evaluated two kinetic methods for determining total amylase activity and isoenzyme composition in serum. Stability studies of reagents for measuring total activity indicate that reagents containing 4-nitrophenyl-alpha-glucosides or enzyme-linked reagents can be stored only for seven days at 4 degrees C. Methods based on 4-nitrophenyl-alpha-glucoside substrates cannot be used if the reagent a...

The current objective of the study is to evaluate the α-amylase inhibitory activity of butein and tricetin using in silico docking studies. In this perspective, butein and tricetin ligands were prepared for the docking evaluation. Acarbose, a known α-amylase inhibitor was used as the standard. In silico docking studies were carried out using recent version of AutoDock 4.2, which has the basic p...

The present research aimed to investigate the phytochemical bioactive constituents and proximate composition of methanol extract Kigelia africana Annona senegalensis stem bark, as well its in vitro antidiabetic potential. results suggest that presence compounds may be responsible for numerous medicinal capacities these plants, including their abilities. bark extracts K. A. demonstrated strong α...

BACKGROUND In the present study, we tested a 50% ethanolic extract of Orthosiphon stamineus plants and its isolated bioactive compound with respect to their α-glucosidase and α-amylase inhibitory activities. METHODS Bioactive flavonoid sinensetin was isolated from 50% ethanolic extract of Orthosiphon stamineus. The structure of this pure compound was determined on the NMR data and the α-gluco...

Diabetes mellitus is a multifactorial disease. The nature has a plentiful sources as a remeady for this slow-killing condition. The aim of the present to assess the medicinal plants for anti-diabetic activity by using -amylase and -glucosidase inhibition assay. Anti-diabeticactivities of medicinal plants weredetermined by -amylase and -glucosidase inhibition assay. Results revealed that methono...

To identify the muscarinic subtype present on the rat pancreatic acinar cell, we examined the effects of different muscarinic receptor antagonists on amylase secretion and proteolytic zymogen processing in isolated rat pancreatic acini. Maximal zymogen processing required a concentration of carbachol 10- to 100-fold greater (10-3 M) than that required for maximal amylase secretion (10-5 M). Alt...