The present study was carried out to examine whether nasal strip application would improve the exercise-induced arterial hypoxemia and hypercapnia, diminish anaerobic metabolism, and modify the incidence of exercise-induced pulmonary hemorrhage (EIPH) in horses. Two sets of experiments, control and nasal strip experiments, were carried out on seven healthy, sound, exercise-trained Thoroughbred ...

BACKGROUND A previous study associated CD34(+) levels with NYHA functional class in heart failure patients. The aim of this study was to correlate CD34(+) levels to exercise capacity, functional class, quality of life and norepinephrine in heart failure patients. METHODS Twenty three sedentary patients (52 +/- 7 years, 78% male) answered the Minnesota Living with Heart Failure Questionnaire a...

Rees BB, Boily P, Williamson LAC. Exerciseand hypoxiainduced anaerobic metabolism and recovery: a student laboratory exercise using teleost fish. Adv Physiol Educ 33: 72–77, 2009; doi:10.1152/advan.90188.2008.—Anaerobic metabolism is recruited in vertebrates under conditions of intense exercise or lowered environmental oxygen availability (hypoxia), typically resulting in the accumulation of la...

The fiddler crab, Uca pugilator, used sideways octapedal locomotion during 15 min of treadmill exercise. At each velocity tested (0-06, 0-11 and O'^kmh") , oxygen consumption (V02) showed only a modest, sluggish elevation; a 'steady-state' was never attained. The highest V02 recorded, O-ZZmlOzg"^", was 4-4 times the resting rate. Net whole body lactate (WBL) was found to increase at a constant ...

A computer model of a skeletal muscle bioenergetic system is used to study the background of the slow component of oxygen consumption V̇O2 on-kinetics in skeletal muscle. Two possible mechanisms are analyzed: inhibition of ATP production by anaerobic glycolysis by progressive cytosol acidification (together with a slow decrease in ATP supply by creatine kinase) and gradual increase of ATP usage ...

BACKGROUND Exercise training is known to improve the shortness of breath experienced by patients with heart disease when the ventilatory pattern becomes abnormal during exercise. However, the precise relationship between breathing patterns and the effect of exercise training has not been elucidated to date. We evaluated the relationship between the effect of exercise training on exercise tolera...

The objective of the present study was to determine the variability of the arterio-venous O(2) concentration difference [C(a-v)O(2)] at anaerobic threshold and at peak oxygen uptake (VO(2)) during a progressively increasing cycle ergometer exercise test, with the purpose of assessing the possible error in estimating stroke volume from measurements of VO(2) alone. We sampled mixed venous and sys...

REDUCED ACTIVITY OF THE POTENT ANABOLIC EFFECTORS insulin-like growth factor-I (IGF-I) and fibroblast growth factor-2 (FGF-2), play a role in aging associated muscle loss. The effect of fitness level on IGF-I and FGF-2 responses to all-out anaerobic exercise in older men was studied. Twenty four healthy older males: 12 higher fit (58 ± 1y) and 12 lower fit (59 ± 1y) underwent the Wingate anaero...

BACKGROUND Research on the effects of exercise on immune function, has a wide range of sporting activities. Study on the long-term effects of regular exercise on serum levels of cytokines such as interleukin-17 have shown that moderate and regular exercise, has an important role in the prevention and treatment of many diseases. OBJECTIVES Exhaustive exercise has a deep effect on cellular, hum...