Wheel/rail contact simulation is one of the most complicated problems in the modeling of railway vehicles. The wheel/rail interaction plays a unique role in rail vehicle dynamics. In this paper, the dynamic response of the wheel on irregular rail track is analyzed with analytical approach using the method of Multiple Scales (MMS). The Hertzian contact theory is used to obtain the relationshi...

-The multi-criteria decision making (MCDM)problems with fuzzy preference information on alternatives are essential problems of the importance of weighting and ranking. In order to solve this problem, Analytical Hierarchy Process(AHP) and fuzzy comprehensive evaluation method are coupled to form a new approach named Fuzzy-AHP.This method is different from the traditional FAHP,which used to facil...

Sorting of particles such as cells is a critical process for many biomedical applications, and it is challenging to integrate it into an analytical microdevice. We report an effective and flexible dielectrophoresis (DEP)-based microfluidic device for continuous sorting of multiple particles in a microchannel. The particle sorter is composed of two components-a DEP focusing unit and a Movable DE...

The quality of water destined for human consumption has been treated as a multivariate property. Since most of the quality parameters are obtained by applying analytical methods, the routine analytical laboratory (responsible for the accuracy of analytical data) has been treated as a process system for water quality estimation. Multivariate tools, based on principal component analysis (PCA) and...

Detection systems rely more and more on on-line or off-line comparison of detected signals with basis signals in order to determine the characteristics of the impinging particles. Unfortunately, these comparisons are very sensitive to the random time shifts that may alter the signal delivered by the detectors. We present two fast algebraic methods to determine the value of the time shift and to...

During the genomic revolution, algorithmic and analytical methods for organizing, integrating, analyzing, and querying biological sequence data proved invaluable. Today, increasing availability of high-throughput data pertaining to functional states of biomolecules, as well as their interactions, enables genome-scale studies of the cell from a systems perspective. The past decade witnessed sign...

Systematic reviews provide the best evidence on the effectiveness of healthcare interventions including quality improvement strategies. The methods of systematic review of individual patient randomised trials of healthcare interventions are well developed. We discuss methodological and practice issues that need to be considered when undertaking systematic reviews of quality improvement strategi...

Unsaturated flow of soils in unsaturated soils is an important problem in geotechnical and geo-environmental engineering. Richards’ equation is often used to model this phenomenon in porous media. Obtaining appropriate solution to this equation therefore provides better means to studying the infiltration into unsaturated soils. Available 5 methods for the solution of Richards’ equation mostly f...