INTRODUCTION Androgenetic alopecia (AGA) is the most common form of hair loss, however current treatment options are limited and moderately effective. In the past few years, there has been an increased interest in deciphering the molecular mechanisms responsible for this disorder, which has opened the possibility of novel treatments that promise to not only stimulate hair growth, but also to in...

Androgenetic alopecia (AGA), or pattern hair loss, is a common disorder in Asian men and women, with a reported incidence of up to 73% among general population. There are several descriptions regarding the characteristics of AGA in patients of European descent. Asian patients with AGA have different types of hair loss and family histories from Europeans, which may affect treatment response. The...

BACKGROUND In the search for alternative agents to oral finasteride and topical minoxidil for the treatment of androgenetic alopecia (AGA), melatonin, a potent antioxidant and growth modulator, was identified as a promising candidate based on in vitro and in vivo studies. MATERIALS AND METHODS One pharmacodynamic study on topical application of melatonin and four clinical pre-post studies wer...


 In recent years, several studies have demonstrated the involvement of intestinal microbiota in immune-mediated diseases such as diabetes, ulcerative colitis, and multiple sclerosis. There are few data on follicular microbiome its role pathogenesis scalp diseases. Some show influence dysbiosis these diseases, manipulation may represent a possible therapeu- tic option. This article reviews...

Patterned hair loss also known as androgenetic alopecia (AGA), is a hereditary androgen dependent disorder characterised by a progressive process that causes a gradual conversion of terminal hair into miniaturized hair defined by various patterns [1]. It is a feature of men who have sufficient circulating androgens. Male pattern hair loss is characterised by its typical bitemporal recession of ...

Three cases of androgen-dependent disease in females with myotonic dystrophy are described. Serum androgens in individuals affected by myotonic dystrophy are known to be lower on average than in normal controls. Despite this these three females developed diseases that are androgen dependent, including acne, hidradenitis suppurativa, androgenetic alopecia and keratosis pilaris. These cases suppo...

BACKGROUND Trichoscopic findings of hair loss have been well described for the differential diagnosis of alopecia; however, critical findings were not thoroughly investigated or compared among all ethnic groups, including Asians. OBJECTIVE We aimed to find any characteristic trichoscopic findings in Korean alopecia patients and to verify whether those findings are closely related to previousl...

CONTEXT Androgenetic alopecia is the most common form of alopecia in men. OBJECTIVE To determine the efficacy and safety of finasteride therapy for patients with androgenetic alopecia. DATA SOURCES MEDLINE, EMBASE, CINAHL, Cochrane Registers, and LILACS were searched for randomized controlled trials reported in any language that evaluated the efficacy and safety of finasteride therapy in co...

The Gulf Journal of Dermatology and Venereology INTRODUCTION Androgenetic alopecia (AGA) is a hereditary and androgen-dependent progressive thinning of the scalp hair in a defined pattern. It is a common dermatological disorder affecting more men and occasionally women, with significant negative impact on their social and psychological well being. AGA commonly begins by 20 years of age and affe...