نتایج جستجو برای: angiotensin receptors
تعداد نتایج: 271145 فیلتر نتایج به سال:
We investigated in Lewis normotensive rats the effect of coronary artery ligation on the expression of cardiac angiotensin-converting enzymes (ACE and ACE 2) and angiotensin II type-1 receptors (AT1a-R) 28 days after myocardial infarction. Losartan, olmesartan, or the vehicle (isotonic saline) was administered via osmotic minipumps for 28 days after coronary artery ligation or sham operation. C...
Angiotensin II receptors are the specific receptors of angiotensin II of the renin-angiotensin system. The existence and role of the receptors in the skin have not been determined. We immunohistochemically studied the expression of angiotensin receptors in the human skin. The results demonstrated the expression of angiotensin type 1 receptor (AT1) in the normal human suprabasal epidermis. The e...
NaCl reabsorption in the medullary thick ascending limb of Henle (MTALH) contributes to NaCl balance and is also responsible for the creation of medullary interstitial hypertonicity. Despite the presence of angiotensin II subtype 1 (AT(1)) receptors in both the luminal and the basolateral plasma membranes of MTALH cells, no information is available on the effect of angiotensin II on NaCl reabso...
The intrathecal (i.t.) injection of substance P (SP) and N-methyl-D-aspartate (NMDA) induce transient nociceptive response by activating neurokinin (NK) 1 NMDA receptors, respectively. We have recently reported that angiotensin (Ang) (1–7), an N-terminal fragment Ang II, could alleviate several types pain including neuropathic inflammatory spinal MAS1. Here, we investigated whether (1–7) can in...
In March 2020, the Coronavirus disease 2019 (COVID-19) pandemic was announced by World Health Organization (WHO). A novel strain of coronavirus, recently named Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) created disease, which showed symptoms similar to SARS. The virus's bond determines its pathogenesis with host's cell receptors, mainly ngiotensin- C onverting E nzyme (ACE2) . It ...
The present study tested the hypothesis that angiotensin II plays a role in the regulation of placental vascular tone, which contributes to hypertension in preeclampsia. Functional and molecular assays were performed in large and micro placental and non-placental vessels from humans and animals. In human placental vessels, angiotensin II induced vasoconstrictions in 78.7% vessels in 155 tests, ...
TSUTSUMI, KEISUKE, AND JUAN M. SAAVEDRA. Characterization and development of angiotensin II receptor subtypes (AT1 and AT,) in rat brain. Am. J. Physiol. 261 (Regulatory Integrative Comp. Physiol. 30): R209-R216, 1991.-Angiotensin II receptor subtypes (AT1 and AT,) were characterized in rat brain by displacement with the specific angiotensin antagonists Du Pont 753 and CGP 42112A, respectively,...
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