The elaboration of a 6,6-spiroacetal scaffold to incorporate a nucleoside unit at the anomeric position is described. The novel spiroacetal-nucleoside hybrids were generated via nucleosidation of acetoxy-spiroacetal with a series of silylated nucleobases under Vorbrüggen conditions.

In the title compound, C(13)H(16)Cl(3)NO(8), the trichloro-acetimidate group is located in an axial postion on the anomeric carbon of the sugar ring.

Dextran-b-polystyrene diblock copolymers forming miscellaneous spherical self-assemblies in water were obtained by chemical modification of the anomeric extremity of a commercial dextran followed by atom transfer radical polymerisation of styrene.

Acetylation and CrO(3) oxidation in acetic acid (Angyal and James, Aust. J. Chem. 23: 1209-1221, 1970) was applied to 18 different glyceroglycolipids and glycosphingolipids of known structure. The lipids studied contained from one to five pyranosic monosaccharide units including alpha- and beta-linked glucose, galactose, mannose, and N-acetylgalactosamine and beta-linked N-acetylglucosamine. Mo...

Complex mixtures of carbohydrates pose distinct challenges in routine and high-throughput analysis, so that only a few carbohydrate components are routinely resolved and identified in biofluids, extracts, foods and other complex mixtures. Here, we conduct precise measurements of (1)H and (13)C anomeric chemical shifts to construct a reference library of specific carbohydrate signals with high-r...