We developed a transgenic mouse to permit conditional and selective ablation of hair cells in the adult mouse utricle by inserting the human diphtheria toxin receptor (DTR) gene into the Pou4f3 gene, which encodes a hair cell-specific transcription factor. In adult wild-type mice, administration of diphtheria toxin (DT) caused no significant hair cell loss. In adult Pou4f3(+/DTR) mice, DT treat...

BACKGROUND The large caliber of head hair in hair transplantation imparts a coarse hairline, whereas natural hairlines are typically softer. In hirsute individuals, transplantation of leg hair to the hairline may result in a superior aesthetic appearance. OBSERVATION A total of 1025 leg hair follicles in 1 patient were grafted to an area 0.5 to 1.0 cm in front of and 0.5 to 1.0 cm internal to...

This work presents a simple, stable and fast hair simulation system for interactive graphics applications whose CPU budget for hair simulation is small. Our main contribution is a hair-head collision method that has very little CPU cost and simulates the volumetric effect of hair resting on top of each other without the need for hair-hair collision. We also present a simulation-based hair styli...

Hair restoration is a highly sophisticated subspecialty that offers significant relief to patients with hair loss. An improved understanding of the aesthetics of hair loss and cosmetic hair restoration, hair anatomy and physiology, and the development of microvascular surgical instrumentation has revolutionized the approach to surgical hair restoration since the original description. Additional...

Hair is one of the crucial elements in representing believable digital humans. It is one of the most challenging elements, too, due to the large number of hairs on a human head, their length, and their complex interactions. Hair appearance, in rendering and simulation, is dominated by collective properties, yet most of the current approaches model individual hairs. In this paper we build on the...

Hair graying and hair loss are prominent and common characteristics of the elderly population. In some individuals these processes can significantly impact their quality of life, leading to depression, anxiety and other serious mental health problems. Accordingly, there has been much interest in understanding the complex physiological changes within the hair follicle in the aging individual. It...

The regulation of the periodic regeneration of hair follicles is complicated. Although Wnt10b has been reported to induce hair follicle regeneration, the characteristics of induced hair follicles, especially the target cells of Wnt10b, have not yet been clearly elucidated. Thus, we systematically evaluated the expression and proliferation patterns of Wnt10b-induced hair follicles. We found that...

A major outstanding goal of vestibular neuroscience is to understand the distinctive functional roles of type I and type II hair cells. One important question is whether these two hair cell types differ in bundle structure. To address this, we have developed methods to characterize stereocilia numbers on identified type I and type II hair cells in the utricle of a turtle, Trachemys scripta. Our...

Overall protein integrity is an important hallmark of healthy hair and has a great impact on the cosmetic value of the hair shaft. Hair is comprised of ~80% protein (predominantly αkeratin) and is not regenerative after it exits the scalp. Therefore, protection of the native hair structure on the protein and fiber levels is critical to ensure good cosmetic properties of the hair. Consumer pract...

The main challenge in an automated diagnostic system for the early diagnosis of melanoma is the correct segmentation and classification of moles, often occluded by hair in images obtained with a dermoscope. Hair occlusion causes segmentation algorithms to fail to identify the correct nevus border, and can cause errors in estimating texture measures. We present a new method to identify hair in d...