Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease entity usually occurring in children. In the present study a case of TINU syndrome in an elderly patient is described and relevant literature is reviewed. A 61-year-old man presented with bilateral flank pain, urinary frequency, and foamy urine. A kidney ultrasonography revealed an increase in kidney parenchyma echogenic...

purpose: to report a case of ciliary body medulloepithelioma presenting as granulomatous uveitis.   patient and finding: a 3-year-old girl presented with chronic granulomatous anterior uveitis in the right eye following unilateral cataract extraction and iol implantation which was unresponsive to topical steroids and intra-vitreal injection of vancomycin and triamcinolone acetonide. one month l...

Autoimmunity directed against retinal or choroidal antigens has been suggested to play a role in the chorioretinal lesions observed in patients with Fuchs' heterochromic cyclitis. This hypothesis was addressed and patients with Fuchs' heterochromic cyclitis were tested for cellular immunity (migration inhibitory factor assay) against human retinal S-antigen. A significantly higher percentage of...

AIMS To establish the frequency and risk factors for visual loss in a primary referral cohort of hospital patients with uveitis. METHODS 561 consecutive uveitis patients attending three district hospitals were recruited and the acuity at the end of the study period recorded. A retrospective case-control study of risk factors for visual loss (permanent loss of acuity <6/9) was performed. Risk ...

Twenty-eight cases of acute anterior uveitis in which raised antibody titres indicated yersinia infection as a possible causative factor in the disease were studied retrospectively. In most cases the antibodies belonged to the IgA class; in only 6 patients did the presence of IgM class antibodies indicate recent infection. In half the cases also antibody titres against Chlamydia were raised. Th...

1. Byles DB, Frith P, Salmon JF. Anterior uveitis as a side effect of topical brimonidine. Am J Ophthalmol. 2000;130:287-291. 2. Goyal R, Ram AR. Brimonidine tartrate 0.2% (Alphagan) associated granulomatous anterior uveitis. Eye. 2000;14:908-910. 3. Cantor LB. The evolving pharmacotherapeutic profile of brimonidine, an alpha 2-adrenergic agonist, after four years of continuous use. Expert Opin...

This paper presents for the first time documented evidence, clinical details, and photographic illustrations of metipranolol-associated granulomatous anterior uveitis in 26 eyes of 15 patients being treated for glaucoma. There were 56 episodes of granulomatous anterior uveitis, all associated with large (mutton-fat) keratic precipitates, flare, cells, and 'white eyes' (except in seven episodes)...

The induced expression of HLA antigens on a variety of tissues involved in autoimmune diseases has been reported by several groups. In this study, we have examined the expression of HLA antigens in iris biopsy specimens from patients with anterior uveitis and compared them to patients with noninflammatory senile cataracts. In addition, we measured the levels of gamma interferon in the aqueous h...