objective: the present study was undertaken to evaluate anti-depressant activity of myristica fragrans(ms). materials and methods: male wistar rats were subjected to imipramine and herbal extract ofms for their antidepressant activity using forced swimming test (fst), reserpine reversal test (rrt), haloperidol-induced catalepsy (hic), and pentobarbitone sleeping time (pst). results: administrat...

Available evidence suggests that anti-depressant treatment can precipitate mania or hypomania in bipolar patients (Wehr and Goodwin, 1987). This is thought to be related to an increase in the neurotransmitters norepinephrine and/or dopamine (Bunny et al., 1972). Recently interest has focused on mania induced by fluoxetine, a selective inhibitor of serotonin reuptake. Here we report on a case wi...

Objectives: The aim of the study is to evaluate antidepressant activity ethanolic extract leaves Moringa oleifera L. (EEMO) on albino mice. Methods: anti-depressant was evaluated using forced swimming test (FST) and tail suspension (TST). Healthy mice were individually swim inside a vertical glass cylinder. Climbing, swimming, immobility tested recorded. In TST, suspended string held by metal s...

Introduction: Depression disorder has significant potential morbidity and mortality, contributing to suicide, incidence adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, lost work time. Objectives: The present study was designed the anti-depressant activity seeds extract Zanthoxylum armatum using a forced swim test tail suspension on Swiss albino m...