Continued investigation of the marine alga Laurencia claviformis has led to the isolation of pacifenol, a halogenated sesquiterpene as the major metabolite. The microbial transformation of pacifenol is reported. It was cultivated with a marine strain of Penicillium brevicompactum yielding a new compound. The structure was elucidated on the basis of spectroscopic data. The anti-microbial activit...

Gaegurin 5 (GGN5) is a cationic 24-residue anti-microbial peptide isolated from the skin of a Korean frog, Rana rugosa. It contains a central proline residue and an intra-residue disulphide bridge in its C-terminus, which are common to the anti-microbial peptides found in Ranidae. We determined the solution structure of GGN5 bound to SDS micelles for the first time and investigated the role of ...

medicinal plants are a source of great economic value all over the world. nature has bestowed on us a very rich botanical wealth and large number of diverse types of plants grows in different parts of the country. in this study the in vitro antimicrobial activity of crude ethanolic, methanolic and water extracts of the stem bark of o.basilicum were investigated. the extracts exhibited antimicro...

Artocarpus camansi (AC) has been long used by Indonesian local people as food and traditional medicine. This study aims to explain the relationship between use of AC a ingredient medicine its bioactivity. The method in writing this article is literature on various scientific articles published online at Google Scholar using AC, uses bioactivities. results obtained were synthesized so be able bo...

Objectives: Evaluation of therapeutic effects of Carum copticum (C. copticum) has been the subject of several studies in recent years. Thymol the major component of C. copticum is a widely known anti-microbial agent. In this study, the antibacterial and anti viral activities of essential oil of C. copticum fruit were determined. Materials and Methods: Essential oil of C. copticum was analyzed ...

BACKGROUND Bacterial infections of the gastrointestinal tract (GIT) cause vomiting, diarrhoea and even systemic disease. There is a need for the development of natural products into alternative and safer medicines. OBJECTIVES This study evaluated the anti-microbial activity of extracts prepared from berries, leaves, bark and roots of the edible plant Grewia flava. METHODS The anti-bacterial...

the aim of this study was to assess the effects of heavy metal tolerant soil microbes inoculation on growth and metal uptake of pearl millet (pennisetum glaucum), couch grass (triticum repens) and alfalfa (medicago sativa) in a soil spiked (and subsequently aged) with increasing concentrations of pb. a soil sample (soil 1) was spiked with increasing (0 to 1500 mg/kg) concentrations of pb and in...

Microbial biotransformation is a great model system to produce drugs and biologically active compounds. In this study, we elucidated the fermentation and production of an anti-cancer agent from a microbial process for regiospecific hydroxylation of resveratrol. Among the strains examined, a potent strain showed high regiospecific hydroxylation activity to produce piceatannol. In a 5 L (w/v 3 L)...

Aim- To review comprehensive literature on Bhurjah (Betula utilis D. Don) w.s.r. to its therapeutic activity. Background- is a very ancient traditional medicine, commonly known as Bhojpatra in Hindi and Himalayan birch English. Bark of Betula was used times for writing Sanskrit texts. Ancient sages write down manuscripts those remains unaffected by microbes, environmental biological factors. Fr...