BACKGROUND The purpose of this study was to evaluate the correlations of thyroid antibody and thyroid hormone in postradiotherapy (post-RT) patients with nasopharyngeal carcinoma (NPC). METHODS Serum thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), thyroperoxidase antibody (anti-TPO), and thyroglobulin antibody (anti-TG) levels of 55 patients with NPC were...

background: thyroid autoimmunity may be linked to infertility, in both thyrotropin (tsh)-dependent and tsh-independent fashion. the aim of the present study was to assess this presumed reciprocal relationship of thyroid autoimmunity and pregnancy. methods: tsh and antithyroid peroxidase autoantibodies (anti-tpo) were evaluated retrospectively over an eight-year period in 444 greek women who had...

OBJECTIVE Interferon-beta (IFN-β) is widely used in patients with multiple sclerosis (MS), a demyelinating disease of the central nervous system. High incidence of thyroid dysfunction has been reported after administration of IFN-β in MS patients. The aim of this study was to assess the effect of IFN-β1a therapy on simultaneous thyroid and salivary gland function in patients with MS using quant...

BACKGROUND Thyroid autoimmunity has been suggested as a risk factor for atherosclerosis independent of thyroid function in several studies. The aim of this study was to investigate whether thyroid autoimmunity had any effect on hyperlipidaemia, obesity and abdominal obesity independent of thyroid function. MATERIAL AND METHODS 184 premenopausal female patients with Hashimoto's thyroiditis (HT...

The endocrine function and pituitary imaging in Sheehan's syndrome more than 30 years after causative events were evaluated. Magnetic resonance imaging (MRI), a combined anterior pituitary test, plasma vasopressin-to-osmolality adaptation study, and antithyroid and antipituitary cell antibody measurement were performed in 6 women with Sheehan's syndrome. The interval from delivery to the onset ...

BACKGROUND Neurofibromatosis type 1 is an autosomal dominant neurocutaneous disorder in which the coexistence of autoimmune thyroiditis and thyroid gland tumours has been reported previously. AIMS To determine the thyroid function and autoimmune thyroid diseases in neurofibromatosis type 1 patients in order to identify the possible association between neurofibromatosis type 1 and thyroid dise...

Familial Mediterranean Fever (FMF) is an auto inflammatory disease[1] and also it can occur together with autoimmune disorders, such as Behçet's syndrome and systemic Lupus erythematosus[2,3]. Here, we present Familial Mediterranean fever and Hashimoto’s thyroiditis association in a 10-year-old girl. This girl was admitted to our hospital with a history of intermittent abdominal pain, fever, he...

Background: Type 1 diabetes mellitus (T1DM) as an autoimmune disorder is associated with other autoimmune diseases such as autoimmune thyroid (AIT) disease. The aim of this study was to determine the prevalence of AIT in children who were referred to Amirkola Endocrine Clinic (north of Iran). Methods: This cross-sectional study was carried out on 100 diabetic children aged 1-15 years during ...

Introduction: Melasma is a common acquired hypermelanosis seen mainly in women which occurs on the sun-exposed skin of the face. The exact cause of melasma is unknown. The majority of the cases are attributed to pregnancy, combined oral contraceptive pills, genetic factors, sun exposure, use of cosmetic products, thyroid disorders and anti-convulsant drugs. This study was performed to evaluate ...

Fetal goiter is an uncommon, serious problem during pregnancy. Careful routine antenatal ultrasound screening can find out an intrauterine fetal goiter. Fetal goiter has an incidence of 1:40000 live births (1). 80% of cases are caused by dysgenesis of the thyroid gland. The rest 5% and 15% are due to hypothalamohypophyseal abnormalities and dyshormonogenesis, respectively. 8% of cases are due t...