نتایج جستجو برای: anticoagulants
تعداد نتایج: 15089 فیلتر نتایج به سال:
Prophylactic anticoagulant treatment prior to mitral valvotomy was first recommended by Storm and Hansen (1955). Several authors have since confirmed that this measure significantly reduces the incidence of operative and post-operative embolism. But this dreaded complication was entirely abolished only in Storm and Hansen's series and in the first series reported by Miscall et al. (1962). In al...
Although their first application in clinical practice occurred in the 1940s, vitamin K antagonists remain the only form of oral anticoagulant medication approved for long-term use. Although the available vitamin K antagonists are highly effective for the prevention and/or treatment of most thrombotic disease, the significant interpatient and intrapatient variability in dose-response, the narrow...
Warfarin, acenocoumarol, and phenprocoumon are among the major anticoagulant drugs worldwide. Because of their low therapeutic index and serious adverse reactions (ADRs), their wide use, and their varying kinetics and pharmacogenetic dependence, it is of great importance to explore further possibilities to forecast the dose beyond conventional INR measurements. Here, we describe particulars of ...
Background: The role of anticoagulant medications in preventing placental mediated pregnancy complications in patients with and without thrombophilia has not been investigated well. One underlying cause is associated with adverse effects of anticoagulants in pregnancy including teratogenicity, complexities in dosing and management of anticoagulants during pregnancy and labor. We aimed to assess...
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