Objective: To analyse the antidiarrhoeal activity of Hemidesmatus indicus (L) R. Br root aqueous (HIRAE) and ethanolic (HIREE) extracts. Methods: HIRAE and HIREE at the dose of 100 and 200mg/kg bw was used to assess antidiarrheal activity in albino rats. Antidiarrheal activity was studied with reference to castor oil diarrhea for assessing faecal score, intestinal transit and enteropooling and ...

A 22 year old insulin dependent diabetic with high volume, secretory chronic diarrhoea refractory to standard andiarrhoeal drugs was treated with the somatostatin analogue octreotide, 50 micrograms twice daily by subcutaneous injection. She improved markedly with a decrease in mean stool weight from 1170 g/24 h range 440-2900 g) to 440 g/24 h (range 180-800 g) (p < 0.05). Stool frequency also d...

Cyperus rotundus Linn. (Cyperaceae) vernacularly called ‘Nagarmotha’ is an Indian medicinal plant demonstrated to exert multiple health benefits. This plant grows naturally in tropical, subtropical and temperate regions. It is traditionally used for various purposes including as an antidiarrhoeal, antidiabetic, antipyretic, antiinflammatory, antimalarial and for treatment of stomach and bowel d...

Swietenia macrophylla King (Meliaceae) is an endangered and medicinally important plant indigenous to tropical and subtropical regions of the World. S. macrophylla has been widely used in folk medicine to treat various diseases. The review reveals that limonoids and its derivatives are the major constituents of S. macrophylla. There are several data in the literature indicating a great variety ...

Loperamide, a mu opioid receptor agonist, which is commonly used as an antidiarrhoeal agent has been reported to possess analgesic activity after intrathecal administration. However, the exact analgesic profile, i.e., onset, duration and intensity of analgesia in relation to morphine is not fully known. In the present study, the acute analgesic effect of loperamide (5 microg) was compared with ...

Strychnos potatorum Linn.F. is a medicinally important endangered forest tree species which belongs to Loganiaceae and is also known as nirmali and clearing nut tree. In traditional medicinal systems like Ayurveda, Siddha and Greek, the plant parts are used for treating eye and urinary tract infections; gonorrhoea and kidney troubles, leucorrhoea, tuberculosis, diabetes, venereal diseases and a...

A method is described for the measurement of hydrogen in expired air, using an electrochemical detector. The apparatus is simple to use and sensitive. Its application is illustrated by studies of small bowel transit time made by measuring the time between oral ingestion of the unabsorbable carbohydrate lactulose and a rise in the concentration of hydrogen in expired air. In 20 control subjects ...