brown alga, turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). the extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. minimal inhibitory concentration was determined for active extracts by broth dilution method. the antiviral activity and cytotoxicity of the extracts were tested in human embryon...

The methanol leaf extracts of Acacia nilotica, Sida cordifolia, Tinospora cordifolia, Withania somnifer and Ziziphus mauritiana are ethnomedicinally important showed significant antibacterial and activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Staphylococcus aureus and Xanthomonas axonopodis pv. malvacearum and antifungal activity against Aspergillus flavus, Dresc...

Background: In recent years, drug resistance to human pathogenic fungi has been increased. Medicinal plants are one way to overcome antibiotic resistance. The aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of Candida albicans. Methods: This study was done in the Microbiology Lab of Shahid Bahonar University of Kerman, Iran in 2...

Sponges are the simplest multicellular animals that lack defense mechanisms and rely on chemical defense  that have been used by mankind to develop antimicrobial drugs against diseases.  The present study was designed to demonstrate the antibacterial and antifungal activities of marine sponge Dysidea pallescens semipolar and nonpolar extracts. In this study, D. pallescens were collected from He...

Defensins are a large family of small, cationic, cysteine-rich proteins that are part of the defense arsenal that plants use for protection against potentially damaging fungal infections. The plant defensin NaD1 from Nicotiana alata is a potent antifungal protein that inhibits growth and kills a variety of fungal pathogens that affect both plant and animal (human) hosts. Some serine protease in...

during the past decade, natural plant products as environmentally safe option have received attention for controlling phytopathogenic diseases. investigation of plants containing natural antimicrobial metabolites for plant protection has been recognized as a desirable method of disease control. the fungus fusarium oxysporum causes diseases such as root rot, damping off and fusarium wilt and it ...

background: emergence of antimicrobial resistance toward a number of conventional antibiotics has triggered the search for antimicrobial agents from a variety of sources including the marine environment. objectives: the aim of this study was to evaluate the antimicrobial potential of holothuria leucospilota from qeshm and kharg islands against some selected bacteria and fungi. materials and met...

In the present study quantitative structure activity relationship studies were performed on a series of N-{(1H-Benzo[d] Imidazol-1-yl) (Phenyl) Methylene} Benzenamine analogues as antifungal activity using Chem Office ultra 8.0.3. Multiple linear regression analysis was performed to derive quantitative structure activity relationship models which were further evaluated internally as well as ext...

OBJECTIVES Invasive mould infections are associated with a high mortality rate and the emergence of MDR moulds is of particular concern. Calcineurin and its chaperone, the heat shock protein 90 (Hsp90), represent an important pathway for fungal virulence that can be targeted at different levels. We investigated the antifungal activity of compounds directly or indirectly targeting the Hsp90-calc...