Colitis is a very complex disease entity with several etiologic and pathogenesis charactistics. It may have acute or chronic forms that may be with significant morbidity and negative effect on the quality of life of the patient. While the most common and recognizable forms are those of infectious etiologies, however, other forms include ulcerative, Crohn’s, immunologic, vascular, pseudo membran...

pathogenesis of various circulatory and neurodegenerative disorders such as thrombosis, atherosclerosis and Alzheimer’s disease, which is now thought to have an inflammatory base. The development of antiinflammatory agents which prevent the accumulation of leucocytes, platelet activation or lost of function of the vessel wall, could constitute new therapeutic strategies for the control of these...

quercetin is a dietary flavonoid which has anti-inflammatory effects. this study aimed to evaluate the influence of quercetin on histopathological aspects and airway epithelium in  allergic airway  inflammation mice model. twenty-eight balb/c mice were randomly divided into four groups: group i (control), group ii (untreated mice with allergic airway inflammation), group iii (allergic airway in...

Chromolaena odorata L. or C. is a weed that found in tropical continents . Leaves, roots and flowers of have been used as medicinal plants for centuries. Preliminary phytochemical screening showed the chemical composition its extracts having phenolic compounds such flavonoids, saponins, tannins steroids. The total (TPC) are acknowledged biochemical activities antiinflammatory, antiviral, antimi...

A new series of tetrahydroindeno[1,2-b]pyrrole-3-carboxylate derivatives(4) were synthesized by reaction of 5-amino-2-mercapto benzimidazole with 1,3-dicarbonyls and activated carbonyl compounds using ceric ammonium nitrate catalyst by a three component one-pot reaction. Structures of these compounds were established on the basis of infrared spectroscopy, proton nuclear magnetic resonance, carb...

Concomitant administration of certain fluoroquinolone antimicrobials and nonsteroidal antiinflammatory agents (NSAIDs) induces serious convulsion in humans. There are differences in convulsive activity among fluoroquinolones and in the potentiation of fluoroquinolone-induced convulsion among NSAIDs, but a comprehensive, quantitative comparison has not been carried out. This study evaluates the ...