We conducted a retrospective study of Escherichia coli isolates recovered from human and food animal samples during 1950-2002 to assess historical changes in antimicrobial drug resistance. A total of 1,729 E. coli isolates (983 from humans, 323 from cattle, 138 from chickens, and 285 from pigs) were tested for susceptibility to 15 antimicrobial drugs. A significant upward trend in resistance wa...

BACKGROUND & OBJECTIVE Enteric fever is a major public health problem in India. It is classically caused by Salmonella enterica serotype Typhi. Salmonella enterica serotype Paratyphi A which had been reported less frequently from cases of enteric fever has shown an increasing trend since 1996 in India. There is also variation in the antimicrobial susceptibility of Salmonella Paratyphi A from di...

INTRODUCTION This study was conducted to determine the prevalence of serotypes, virulence factors, and antimicrobial resistance patterns of Shigella spp. in Beijing, China, from 2004 to 2011. METHODOLOGY Real-time PCR assays were used to detect virulent genes, and the Kirby-Bauer disk diffusion method was used to evaluate antimicrobial resistance. RESULTS Among the total of 1,652 Shigella i...

Background: Wound infection gaining utmost importance day by because of emergence drug resistant bacteria. Objective: This study was carried out to see the pattern aerobic bacterial pathogens along with MRSA and ESBL producing strains causing wound infection. Methodology: cross sectional conducted from May 2010 April 2011. swabs were taken patients suffering infections admitted in different sur...

conclusions the clinical klebsiella strains isolated from lahore region, pakistan exhibited resistance to most commonly used antibiotics, which can be a serious threat to public health. the study reported some potential actinomycetes strains, which exhibit promising activity against multidrug resistant klebsiella strains. results the isolated klebsiella strains showed resistance against most of...

Antimicrobial resistance in pathogenic bacteria has become a serious public health concern as infections with multi-drug resistant bacteria are becoming increasingly difficult to treat. In a recent publication by Hatosy and Martiny, the diversity of antimicrobial resistance genes in marine systems was explored using functional metagenomics. Work from these authors, as well as other studies of a...

BACKGROUND AND OBJECTIVES The appearance of antibiotic resistance in Streptococcus pneumoniae has raised a global concern over the past three decades. This study was conducted to determine the antimicrobial susceptibility of S. pneumoniae isolated from patients in Children´s Medical Center (CMC) Hospital during 2001 to 2011. MATERIALS AND METHODS During the 11 years period, a total of 194 S. ...

The fitness effects of a mutation can depend, sometimes dramatically, on genetic background; this phenomenon is often referred to as "epistasis." Epistasis can have important practical consequences in the context of antimicrobial resistance (AMR). For example, genetic background plays an important role in determining the costs of resistance, and hence in whether resistance will persist in the a...