نتایج جستجو برای: antioxidant defence system
تعداد نتایج: 2327018 فیلتر نتایج به سال:
Cederberg, J. 2001. Oxidative stress, antioxidative defence and outcome of gestation in experimental diabetic pregnancy. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1008. 66 pp. Uppsala. ISBN 91-554-4960-3. Maternal type 1 diabetes is associated with an increased risk for foetal malformations. The mechanism by which diabetes is t...
Inefficient chaperone activity in endoplasmic reticulum (ER) causes accumulation of unfolded proteins and is called ER stress, which triggers the unfolded protein response. For proper oxidative protein folding, reactive oxygen species (ROS) such as H2O2 are produced in the ER. Although the role of ROS during abiotic stresses such as salinity is well documented, the role of ER-related ROS produc...
introduction: in major b -thalassemia impaired biosynthesis of beta hemoglobin leads to accumulation of unpaired alpha hemoglobin chain. an iron overload generates oxygen-free radicals which ultimately leads to tissue injury. the aim of this investigation was to evaluate serum antioxidants in patients with major b -thalassemia and those with minor thalassemia in comparison with respective age ...
Under usual conditions, the production of reactive free radicals and their elimination are in a dynamic equilibrium. This balance could be disturbed when the generation of free radicals becomes higher than the protection capacity of systemic antioxidant defence. The impaired equilibrium in favour of oxidants is named oxidative stress and it is involved in the pathogenesis of numerous diseases, ...
Background & Aims: Sea urchin immune responses are directly exposed to potentially pathogenic microorganisms and develop defence responses mainly based on immunocytes and humoral factors contained in the coelomic fluid. In addition, the polyhydroxylated 1, 4-naphthoquinone pigments are found to possess excellent antimicrobial, antialgal and antioxidant activities. The present ...
BACKGROUND Plant-based diets rich in fruit and vegetables can prevent development of several chronic age-related diseases. However, the mechanisms behind this protective effect are not elucidated. We have tested the hypothesis that intake of antioxidant-rich foods can affect groups of genes associated with cellular stress defence in human blood cells. TRIAL REGISTRATION NUMBER NCT00520819 htt...
In vertebrates, antioxidant defences comprise a mixture of endogenously produced components and exogenously obtained antioxidants that are derived mostly from the diet. It has been suggested that early-life micronutritional conditions might influence the way in which the antioxidant defence system operates, which could enable individuals to adjust the activity of the endogenous and exogenous co...
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