Total alcoholic extract of Desmodium gangeticum, which exhibited significant anti-inflammatory activity, was evaluated for the possible mode of action by studying its antioxidant potential in adjuvant-induced arthritic rats. Activity guided fractionation and isolation were carried out. The phenolics fraction showed maximum potency. Solid phase extraction followed by preparative HPLC of the acti...

Antioxidant and antifungal activity were determined for the essential oil of Alpinia calcarata Roscoe (Zingiberaceae) rhizomes. Its antioxidant properties were investigated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and thiobarbituric acid reactive substances (TBARS) assay. Butylated hydroxy toluene (BHT) and vitamin E served as positive controls. Antifungal activ...

The therapeutic potential of leaf extract of Bryophyllum pinnatum was screened for in vitro antioxidant potential and alpha amylase inhibitory action. Antioxidant activity of the extract was evaluated for hydroxyl radical scavenging activity by Fenton reaction, free radical scavenging by hydrogen peroxide scavenging and superoxide scavenging potential. The in vitro alpha amylase inhibition acti...

Chemical modification of chitosan is increasingly studied for its potential of providing new applications of chitosan. Here, a group of novel chitosan quaternary ammonium derivatives containing pyridine or amino-pyridine were designed and successfully synthesized through chemical modification of chitosan. Pyridine and amino-pyridine were used as functional groups to improve the antifungal activ...

In this study, the antioxidant properties of 80 % ethanol extracts of 16 species of plants from Jeju Island in Korea were evaluated using various antioxidant assays, including the DPPH (1,1-Diphenyl-2-pricrylhydrazyl) radical scavenging, superoxide scavenging, xanthine oxidase inhibition and hydrogen peroxide scavenging activities. Among the 16 plant extracts tested, CN-13 showed strong antioxi...

The objective of the study was to investigate the methanol extract of Pavonia zeylanica (MEPZ) against acetaminophen induced hepatotoxicity and antioxidant activity in Wistar albino rats.The methanol extract of pavonia zeylanica (200, and 400 mg/kg body weight) was administered orally to two groups of rats (six animals per group) in order to evaluate the protective effect of the extract in rats...

An antioxidant mechanism of tetrahydrocannabinol (THC) and cannabidiol (CBD) were compared with a simplified model of α-tocopherol, butylhydroxytoluene and hydroxytoluene in order to understand the antioxidant nature of THC and CBD molecules using DFT. The following electronic properties were evaluated: frontier orbitals nature, ionization potential, O-H bond dissociation energy (BDEOH), stabil...

Sweet and sour cherries contain several polyphenols that possess antioxidant and anti-inflammatory properties. Aim of this study was to investigate the effect of the maturity stage on phenol content and biological properties of extract of a local Morello-type of sour cherry (Prunus cerasus L.), “visciola”. The study of total phenol content and total antioxidant potential was associated with the...

Drugs and some chemical agents are known to induce hepatotoxicity in humans which is of great concern to clinicians. Chemical agents are been screen daily for their hepatoprotective properties. Among these chemical agents is vitamin E which has drawn wide attention due to it reported hepatoprotective property as reported by researchers. This study collected and evaluated reports to ascertain th...

the effect of different solvent systems on the extraction of antioxidant and anti radical agents of grape seed was studied. for this purpose 6 different solvent systems with similar polarity and different selectivity were used to prepare grape seed extract. extraction efficiency, reducing activity, radical scavenging property and the effect of each extract on the increase of thermal resistance ...