Effects of extraction solvent namely ethanol, diethylether-chloroform mixture, morphological matrix namely fruit pericarp seed and three ripening stages namely green, yellow and red on antioxidative activity of S. anguivi fruit were studied. Phytochemical screening and assessment of some antioxidative markers were evaluated. Result showed that all samples were endowed with variable amounts of r...

Abstract Diabetes kidney damage (DKD) is a chronic inflammatory disease of the induced with continuous hyperglycemia as most prevalent consequence diabetes. Washingtonia filifera seed oil (WFO) was used traditional medicine to cure various diseases in ancient Saudi. This work carried out investigate potential protective impact WFO against DKD on streptozotocin (STZ)-induced type 2 diabetic mice...

The plant phenolic compounds such as flavonoids, tannins and phenolic acids appeared to be strong antiradical and antioxidant compounds. The number of hydroxy groups and the presence of a 2,3-double bond and orthodiphenolic structure enhance antiradical and antioxidative activity of flavonoids. The glycosylation, blocking the 3-OH group in C-ring, lack of a hydroxy group or the presence of only...

Human PON1 (h-PON1) is a multifaceted enzyme and can hydrolyze (and inactivate) a wide range of substrates. The enzyme shows anti-inflammatory, antioxidative, antiatherogenic, ant-diabetic, antimicrobial, and organophosphate (OP)-detoxifying properties. However, there are certain limitations regarding large-scale production and use of h-PON1 as a therapeutic candidate. These include difficultie...

Transaldolase, the key enzyme of pentose-phosphate pathway, plays an important role in plant growth and defense. Seed germination is a factor that influences cultivation Aquilaria sinensis, source agarwood, which widely used as traditional medicine, perfume incenses. However, little known about function transaldolase abscisic acid (ABA) signaling-mediated seed germination. In present study, ful...

A soluble viscous protein was purified from yam (Dioscorea opposita Thunb.) tuber mucilage tororo by chromatographic steps, and its functional properties were estimated. The purified dioscorin having the molecular weight of about 200 kDa exhibited high scavenging activities against hydroxyl radicals (IC50 = 195.1 microg/ml) and superoxide anion radicals (IC50 = 92.7 microg/ml). Moreover, it sho...

Protein isolates of pumpkin (Cucurbita pepo L) seeds were hydrolyzed by acid protease to prepare antioxidative peptides. The hydrolysis conditions were optimized through Box-Behnken experimental design combined with response surface method (RSM). The second-order model, developed for the DPPH radical scavenging activity of pumpkin seed hydrolysates, showed good fit with the experiment data with...

Lead (Pb) intoxication may initiate many disorders in human and animals. This study investigates the role of exogenous hydrogen peroxide (H(2)O(2)) in inducing mouse tolerance to Pb exposure. Results showed that the simultaneous application of 1.2 microg H(2)O(2) per kg body weight efficiently protected mice against the Pb-caused injury, as revealed by decreased growth suppression caused by the...

Limitation of reactive oxygen species mediated ischemia-reperfusion (I/R) injury of the lung by vascular immunotargeting of antioxidative enzymes has the potential to become a promising modality for extension of the viability of banked transplantation tissue. The preferential expression of angiotensin-converting-enzyme (ACE) in pulmonary capillaries makes it an ideal target for therapy directed...