Mixed Ni-Al oxide catalytic precursors with different elemental ratios (20, 50, and 80 wt.% Ni0) were synthesized using green supercritical antisolvent co-precipitation (SAS). The obtained metal catalysts characterized in detail by X-ray diffraction (XRD) analysis, atomic pair distribution function (PDF) CO adsorption, high-resolution transmission electron microscopy (HRTEM). It was found that ...

Abstract Background Nanocrystals of any drug are pure solid particles with a mean diameter in nanometer range. Dissolution is crucial factor for absorption medicine case water-insoluble or poorly soluble drugs. The aim this study was to develop nanocrystals hydrophobic drug, Lercanidipine, by addition solvent an antisolvent high-speed homogenization achieve dissolution and solubility enhancemen...

A spray sonocrystallization (SSC) method is described here for the crystallization of pharmaceutical agents that provides for a tunable crystal size and narrow size distribution in the submicron regime. SSC uses a tapped, flow-through ultrasonic horn (20 kHz) to spray very fine droplets of the solute-containing solution into a continuous flow of antisolvent which induces immediate crystallizati...

UNLABELLED BACKGROUND Effective pretreatment is key to achieving high enzymatic saccharification efficiency in processing lignocellulosic biomass to fermentable sugars, biofuels and value-added products. Ionic liquids (ILs), still relatively new class of solvents, are attractive for biomass pretreatment because some demonstrate the rare ability to dissolve all components of lignocellulosic b...

A simple and effective multiresidue method based on precipitation at low temperature followed by matrix solid-phase dispersion-sonication was developed and validated to determine dimethoate, malathion, carbaryl, simazine, terbuthylazine, atrazine and diuron in palm oil using liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS). Liquid-liquid extraction (LLE) followed by low temper...

The supercritical antisolvent (SAS) technique was used to prepare ethyl cellulose/methyl cellulose blends, two biocompatible polymers commonly used as drug carriers in controlled delivery systems. Ethyl cellulose is widely used as a drug carrier. The drug release of the delivery devices can be controlled to some extent by addition of a water-soluble or water swellable polymer, such as methyl ce...

The purpose of the present study was to prepare inclusion complex of domperidone with hydroxylpropyl-β-cyclodextrin in order improved the solubility and hence to increase dissolution of domperidone. An effect of concentration of hydroxylpropyl-β-cyclodextrin on the aqueous solubility of domperidone was determined by phase-solubility method. The aqueous solubility of domperidone increased as a f...

Eutectic solvent can solubilize high amount of some therapeutic compounds. Volatile eutectic solvent is interesting to be used as solvent in the preparation of nanosuspension with emulsion solvent evaporation technique. The mechanism of transformation from the eutectic emulsion to nanosuspension was investigated in this study. The 30% w/w ibuprofen eutectic solution was used as the internal pha...

Typha domingensis pollen is obtained from staminate flowers of plant that edible. In this study, bioactive compounds were extracted using ethanol and methanol with conventional method. Further ultrasonication was applied to the samples improve extraction efficiency. The yield higher (26.3±0.14%) than (25.4±0.3%) applying increased yields significantly (P <0.05). Total phenolic in extract...