نتایج جستجو برای: antitumor activity
تعداد نتایج: 1153846 فیلتر نتایج به سال:
Cancer is a disease that presents as its main characteristic the uncontrolled growth of cells, which currently numerous people annually. The available treatments such chemotherapy cause many adverse effects in cancer patients because it also reaches viable cells body. Plants have wide variety pharmacologically active compounds and are major sources for development new drugs with oncological pot...
objective(s):marine organisms are known as a potential source of natural products, which contain bioactive substances with therapeutic properties. sea cucumbers are prominent among marine organisms because of their dietary and therapeutic applications. in addition, they have capacity of synthesizing saponins molecules and other metabolites with therapeutic properties such as antitumor, antimicr...
A series of sulfamide and triazole benzodiazepines were obtained with the principle of bioisosterism. The p53-murine double minute 2 (MDM2) inhibitory activity and in vitro antitumor activity were evaluated. Most of the novel benzodiazepines exhibited moderate protein binding inhibitory activity. Particularly, triazole benzodiazepines showed good inhibitory activity and antitumor potency. Compo...
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