Obstructive sleep apnea occurs frequently in patients with drug-resistant hypertension. The factors accounting for this observation, however, are unclear. Both conditions demonstrate clinical features suggestive of extracellular fluid volume overload. The aims of this study were to examine whether the spontaneous overnight fluid shift from the legs to the upper body is associated with obstructi...

OBJECTIVE The prevalence of obstructive sleep apnea-hypopnea syndrome (OSAHS) in the general pediatric population ranges from 1% to 3%. However, its prevalence in an unselected population of obese children is unknown. We studied the association between obesity and OSAHS in children diagnosed with the syndrome in a cohort of boys and girls (age range, 2-14 years) referred to the pediatric respir...

Study Objectives. We identified the associated conditions of patients less than 12 months of age who were referred for polysomnogram (PSG) studies. We collated PSG findings and physician interpretation. We determined the correlation between the recommended treatment by the PSG interpreting physician and actual prescribed treatment by the referring or subjects' physician. We determined adherence...

STUDY OBJECTIVES We propose a generation of PSG-derived measures that using entropy can quantify temporal patterns of sleep, and investigate the role of these measures as predictors of hypertension. We also investigate the influence of age on these entropy-based measures as compared to traditional indices. DESIGN AND SETTING Cross-sectional analyses of the association between hypertension sta...

OBJECTIVE Our goal was to validate the WatchPAT in the diagnosis of obstructive sleep apnea. STUDY DESIGN We conducted a prospective, blinded, nonrandomized clinical trial. METHODS Patients with suspected obstructive sleep apnea scheduled for an overnight level I polysomnogram were offered enrollment in a study to compare the WatchPAT (Itamar Ltd, Israel) device with polysomnography. Patien...

OBJECTIVES The aim of the present study is to investigate the efficacy of the Velumount device. METHODS In a prospective cohort study 40 patients were examined with and without Velumount. The apnea-hypopnea index and average esophageal pressure were measured using nocturnal manometry of the upper airways, combined with respiratory polygraphy. The snoring index (1-10) and daytime sleepiness us...

Background Exercise training (ET) is an adjunctive treatment for obstructive sleep apnea (OSA) and its consequences. However, the effects of exercise on heart remodeling are unknown in population with OSA. Objective We investigated effect ET markers diastolic function, parameters, functional capacity patients Methods Sedentary OSA (apnea-hypopnea index, AHI ≥15 events/hr) were randomly assigned...

OBJECTIVE Uvulopalatopharyngoplasty (UPPP) remains one of the most common surgical treatments for patients with obstructive sleep apnea. However, the results after UPPP are unpredictable. The purpose of this meta-analysis is to identify predictors of success after UPPP. DATA SOURCES A literature search was performed utilizing PubMed, EMBASE, SCOPUS, and the Cochrane Library. REVIEW METHODS ...

STUDY OBJECTIVE Changes in sleep-disordered breathing associated with late pregnancy have not previously been systematically investigated; however, a number of case reports indicate exacerbation of obstructive sleep apnea in late pregnancy, often in association with maternal hypertension. We aimed to compare the severity of sleep-disordered breathing and associated maternal blood-pressure respo...