BACKGROUND A "saddle-shaped" mitral annulus with an optimal ratio between annular height and commissural diameter may reduce leaflet and chordal stress and is purported to be conserved across mammalian species. Whether annuloplasty rings maintain this relationship is unknown. METHODS AND RESULTS Twenty-three adult sheep underwent implantation of radiopaque markers on the left ventricle and mi...

the aim of this paper is to generalize the‎‎notion of pseudo-almost valuation domains to arbitrary‎ ‎commutative rings‎. ‎it is shown that the classes of chained rings‎ ‎and pseudo-valuation rings are properly contained in the class of‎ ‎pseudo-almost valuation rings; also the class of pseudo-almost‎ ‎valuation rings is properly contained in the class of quasi-local‎ ‎rings with linearly ordere...

Amyloid precursor protein binding protein-1 (APP-BP1) binds to the carboxyl terminus of amyloid precursor protein and serves as a bipartite activation enzyme for the ubiquitin-like protein, NEDD8. Previously, it has been reported that APP-BP1 rescues the cell cycle S-M checkpoint defect in Ts41 hamster cells, that this rescue is dependent on the interaction of APP-BP1 with hUba3. The exogenous ...

For a ring endomorphism $alpha$ and an $alpha$-derivation $delta$, we introduce a concept, so called skew $pi$-Armendariz ring, that is a generalization of both $pi$-Armendariz rings, and $(alpha,delta)$-compatible skew Armendariz rings. We first observe the basic properties of skew $pi$-Armendariz rings, and extend the class of skew $pi$-Armendariz rings through various ring extensions. We nex...

statement of the problem: implant-retained overdenture can improve the stability of dentures and prevent bone loss. overdenture-wearing patients need special hygiene care. purpose: the aim of this study was to evaluate the effects of various denture cleansers on the retention of dio orange o-rings. method and materials : in this experimental study, 40 dio orange o-rings were divided into 4 grou...

OF THE DISSERTATION Similarity Detection Techniques for Mobile Platform Artifacts by Amruta Gokhale Dissertation Director: Dr. Vinod Ganapathy There has been a tremendous increase in availability and use of mobile apps in recent years. Two dominant mobile platform providers, Apple and Google, have over 1.4 million applications (apps) each in their app markets as of May 2015. Such huge number of...

Subcortically lesioned rats were used as an animal model of some of the neurochemical and behavioral deficits of Alzheimer's disease (AD) to investigate the in vivo expression and metabolism of amyloid precursor protein (APP). Previously, the rapid and persistent induction of APP was described in cerebral cortices after disruption of its cholinergic, serotonergic, or noradrenergic afferents. In...

BACKGROUND Artemisia princeps Pamp (APP), Leonurus japonicas Houtt (LJH), and Gardenia jasminoides Ellis fruit (GJE) have been traditionally used in East Asia to treat women's diseases related to reproductive system. They may attenuate the deterioration of energy, lipid, glucose and bone metabolism by estrogen deficiency. The present study explored the combination of APP, LJH, and GJE to overco...

Amyloid Precursor Protein (APP) is a type I membrane protein that undergoes extensive processing by secretases, including BACE1. Although mutations in APP and genes that regulate processing of APP, such as PSENs and BRI2/ITM2B, cause dementias, the normal function of APP in synaptic transmission, synaptic plasticity and memory formation is poorly understood. To grasp the biochemical mechanisms ...