The defect of the melatonin signaling pathway has been proposed to be one of the key etiopathogenic factors in adolescent idiopathic scoliosis (AIS). A previous report showed that melatonin receptor, MT2, was undetectable in some AIS girls. The present study aimed to investigate whether the abnormal MT2 expression in AIS is quantitative or qualitative. Cultured osteoblasts were obtained from 41...

Dear Sir, Estimation of the biological profile of a deceased is a prerequisite during the identification process of human remains. Highly decomposed, dismembered, and commingled remains are often brought for forensic examination in cases of high-impact bomb blasts, terrorists’ attacks, homicides, airplane, road and train accidents, and natural disasters such as tsunamis, earthquakes, landslides...

OBJECTIVES To characterize a large extended family with early-onset OA of the knee and investigate its associations with the COL2A1 gene. METHODS Phenotype assessments were conducted in a six-generation family to identify individuals affected with OA. Short tandem repeat polymorphic (STRP) markers and DNA sequencing were performed to investigate the involvement of the COL2A1 gene in this fami...

The influence of insulin-like growth factor-2 (IGF2) genotype on total body fat-free mass (FFM), muscle strength, and sustained power (SP) was evaluated repeatedly at approximately 2-yr intervals in two cohorts from the Baltimore Longitudinal Study of Aging. Cohort 1 was comprised of 94 men tested for isometric grip strength and SP. Cohort 2 was comprised of 246 men and 239 women tested for tot...

This study aimed to analyse the effect of growth during a summer break on biomechanical profile of talented swimmers. Twenty-five young swimmers (12 boys and 13 girls) undertook several anthropometric and biomechanical tests at the end of the 2011-2012 season (pre-test) and 10 weeks later at the beginning of the 2012-2013 season (post-test). Height, arm span, hand surface area, and foot surface...

PURPOSE To identify the physiological and anthropometric predictors of rhythmic gymnastics performance, which was defined from the total ranking score of each athlete in a national competition. METHODS Thirty-four rhythmic gymnasts were divided into 2 groups, elite (n = 15) and nonelite (n = 19), and they underwent a battery of anthropometric, physical fitness, and physiological measurements....

a binuclear macrocyclic ligand containing dissimilar n(amine)2o2 and n(imine)2o2 coordination sites sharing two phenolic oxygen atoms, was prepared by cyclic condensation of dialdehyde precursor l1h2 with 1,3-diaminopropane. the ligand includes two propionitrile pendant arms on the amine nitrogen atoms. the homobimetallic complex [znl2zn(oac)]pf6 was synthesized by one step procedure. heterobim...

<span lang="EN-US">Modeling and kinematic analysis are crucial jobs in robotics that entail identifying the position of robot’s joints order to accomplish particular tasks. This article uses an algebraic approach model kinematics a serial link, 5 degrees freedom (DOF) manipulator. The analytical method is compared optimization strategy known as sequential least squares programming (SLSQP)...