This paper presents and evaluates some methods to improve the accuracy of systolic blood pressure measurements based on pulse waveform. A set of measurement was carried out with elderly cardiac surgery patients. The experiments comprised two to five measurements per patient, each including a one-minute follow-up, after which the cuff was slowly inflated over the systolic blood pressure. Systoli...

Traditionally, nitric oxide-mediated alteration in blood vessel tone has been inferred from changes in flow in response to physical and pharmacological interventions using plethysmographic or ultrasonic techniques. We hypothesized that alteration in pulsatile arterial function may represent a more sensitive measure to detect and monitor nitric oxide-mediated modulation of arterial smooth muscle...

BACKGROUND Invasive and continuous blood pressure (BP) monitoring is crucial after cardiac surgery. Accuracy of BP measurement mostly depends on patency of arterial catheter and acceptable waveform. Heparinized saline flush usually used for this purpose may be accompanied by potential heparin adverse effects. OBJECTIVES The aim of this study was to compare heparinized and non-heparinized sali...

We propose a novel technique to implement arbitrary pulse shaping of an ultrashort pulse by intensity-only modulation in the frequency domain. The intensity-only modulation is realized by nonuniformly spaced sampling in the frequency domain. By properly designing the sampling function, multiple pulses in the time domain will be generated with one of which being the desired waveform. The desired...

Motivation Arterial stiffening is both cause and consequence of hypertension,currently the main cause of death in Europe. Hemodynamic metrics such as central pulse pressure (cPP) and pulse wave velocity, which can be non invasively measured, are now known as important predictive factors of diseases and diseases susceptibility. Computational Fluid Dymanic techniques enable an accurate representa...

BACKGROUND Experimental and clinical data suggest that statins exert anti-inflammatory and antiproliferative actions on vasculature beyond their lipid-lowering properties. Whether these pleiotropic effects of statins translate into a beneficial effect on arterial stiffness is not clear. This study aimed to evaluate the potential effects of low-dose atorvastatin treatment on arterial stiffness a...