This study compares the amount of available biomass for wild herbivores (red deer (Cervus elaphus L.), roe (Capreolus capreolus and hare (Lepus europaeus Pallas)) depending on three different types forest silvicultural systems—presented using example beech spruce stands in wintertime. During winter period, provided ten times more than beech. However, metabolizable energy, 7.38 MJ/kg average, wh...

context periodontal plastic surgery can help people improve their lives by addressing aesthetic parameters of their smile. much of what comprises a beautiful and appealing smile is influenced by emotion and personality; however, many structural elements of a smile can be improved through surgical intervention. evidence acquisition the end result often lends significant support to people who wis...

ECM is composed of different collagenous and non-collagenous proteins. Collagen nanofibers play a dominant role in maintaining the biological and structural integrity of various tissues and organs, including bone, skin, tendon, blood vessels, and cartilage. Artificial collagen nanofibers are increasingly significant in numerous tissue engineering applications and seem to be ideal scaffolds for ...

Neuronal behaviour is profoundly influenced by extracellular stimuli in many developmental and regeneration processes. Understanding neuron responses and integration of environmental signals could impact the design of successful therapies for neurodegenerative diseases and nerve injuries. Here, we have investigated the influence of localized extracellular cues on polarization (i.e. axon formati...

Small intestinal submucosa (SIS) is a biodegradable collagen-rich matrix containing functional growth factors. We have previously reported encouraging outcomes for regeneration of an artificial defect in the rodent stomach using SIS grafts, although the muscular layer was diminutive. In this study, we investigated the feasibility of SIS in conjunction with mesenchymal stem cells (MSCs) for rege...

Advanced therapies combating acute and chronic skin wounds are likely to be brought about using our knowledge of regenerative medicine coupled with appropriately tissue-engineered skin substitutes. At the present time, there are no models of an artificial skin that completely replicate normal uninjured skin. Natural biopolymers such as collagen and fibronectin have been investigated as potentia...

Bioactive glass nanoparticles (BG-NPs), based on both ternary (SiO(2)-CaO-P(2)O(5)) and binary (SiO(2)-CaO) systems, were prepared via an optimized sol-gel method. The pH of preparation and the effect of heat treatment temperature were evaluated, as well as the effect of suppressing P in the bioactivity ability of the materials. The morphology and composition of the BG-NPs were studied using FT...

Infections caused by pathogens colonization at wound sites in the process of bone healing are considered as one of the major reasons for the failure of guided bone regeneration (GBR). The objective of this study was to prepare a novel asymmetric collagen/chitosan GBR membrane containing minocycline-loaded chitosan nanoparticles. The morphologies of the membranes and nanoparticles were observed ...

Tendon injuries are commonly met in the emergency department. Unfortunately, tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties. Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (increasing the strength and endurance or anti-adhesio...

Dragon ́s blood tree, a flagship endemic species of Socotra, is threatened with extinction 23 due to lack of natural regeneration, likely because of goat herbivory and/or climatic factors. Loss of 24 dragon ́s blood tree would result in loss of other native flora, heightening the importance of 25 formulating a conservation strategy for it. Although artificial afforestation might be used to offset...