Whole nerve, as well as single fiber, responses in the chorda tympani proper (CT) and glossopharyngeal (NG) nerves of common marmosets were recorded during taste stimulation with three salts, four acids, six bitter compounds and more than 30 sweeteners. We recorded responses of 49 CT and 41 NG taste fibers. The hierarchical cluster analysis distinguished three major clusters in both CT and NG: ...

The appeal of sweet electronic cigarette flavors makes it important to identify the chemical compounds that contribute to their sweetness. While volatile chemicals that produce sweet aromas have been identified in e-liquids, there are no published reports of sugars or artificial sweeteners in commercial e-liquids. However, the sweetener sucralose is marketed as an e-liquid additive to commercia...

Databases The following databases and respective searches were used. • Medline/PubMed: (Sweetening Agents/adverse effects OR Saccharin OR Cyclamate* OR Aspartame OR Acetosulfame OR Acesulfame) AND (Risk Factors OR Risk OR Risk Assessment OR Neoplasm* OR Carcinoma OR Cancer OR Carcinogenic) AND (Etiology/Broad[filter] OR Prognosis/Broad[filter] OR Comparative study OR Comparative studies). • Emb...

Background: The excessive use of artificial sweeteners now a days just to lose weight and remain fit due other reasons without knowing its effects on liver gave me thought conduct this study see whether they are safe or not for health. Aim: To the Aspartame Sucralose size rat hepatocytes compare their choose relatively sweetener routine use. Methods: Fifty adult Wistar albino rats used in were ...

Sweeteners elicit pleasurable sensations with (nutritive) or without (nonnutritive) energy. Nutritive sweeteners (eg, sucrose, fructose) are generally recognized as safe (GRAS) by the Food and Drug Administration (FDA), yet concern exists about increasing sweetener intakes relative to optimal nutrition and health. Dietary quality suffers at intakes above 25% of total energy (the Institutes of M...

BACKGROUND Observational studies have found that dietary glycemic load is positively associated with C-reactive protein (CRP) concentrations in healthy humans, which suggests that the type of carbohydrate ingested influences inflammatory activity. OBJECTIVE We investigated the effect of a diet with a high content of sucrose or artificial sweeteners on the inflammatory markers CRP, haptoglobin...

Pancreatic cancer has an extremely poor prognosis, largely due to a poor record for early detection. Known risk factors for pancreatic cancer include obesity, diet, and diabetes, implicating glucose consumption and regulation as a key player. The role of artificial sweeteners may therefore be pertinent to disease kinetics. The oncogenic impact of artificial sweeteners is a highly controversial ...

The pediatric obesity epidemic has gathered public and political interest recently. People often choose "diet" or artificial sweetened beverages (ASB) to combat this epidemic, but the obesity incidence continues to rise. First, I review the pediatric studies on the effect of ASB consumption with subsequent food intake. Next, I present pediatric studies of chronic ASB consumption and weight chan...