نتایج جستجو برای: aryl grignard

تعداد نتایج: 15617  

2005
Mihaela Corina Iovu Elena E. Sheina Roberto R. Gil Richard D. McCullough

The Grignard metathesis (GRIM) polymerization of 3-alkylthiophenes proceeds by a quasi“living” chain growth mechanism, not by a step growth process. Kinetic studies of the Grignard metathesis polymerization of 2,5-dibromo-3-alkylthiophenes showed that the molecular weight of poly(3-alkylthiophenes) is a function of the molar ratio of the monomer to nickel initiator, and conducting polymers with...

Journal: :Dalton transactions 2013
Jiří Pinkas Ivana Císařová Jiří Kubišta Michal Horáček Martin Lamač

Functional group transformations at the group 4 metallocene framework have been demonstrated, which have provided relatively straightforward access to otherwise synthetically challenging derivatives. The pendant nitrile group in Ti and Zr metallocene complexes of the type [(η(5)-C5Me5)(η(5)-C5H4CMe2CH2CN)MCl2] was converted into an intramolecularly bound ketimido moiety by alkylation, which too...

Journal: :Chemical communications 2008
Yuuki Fujii Jun Terao Yuichiro Kato Nobuaki Kambe

Dimerization of vinyl Grignard reagents and concomitant alkylation with alkyl halides have been achieved by using Cp(2)TiCl(2) as a catalyst.

Journal: :Journal of the American Chemical Society 2008
Alois Fürstner Rubén Martin Helga Krause Günter Seidel Richard Goddard Christian W Lehmann

A series of unprecedented organoiron complexes of the formal oxidation states -2, 0, +1, +2, and +3 is presented, which are largely devoid of stabilizing ligands and, in part, also electronically unsaturated (14-, 16-, 17- and 18-electron counts). Specifically, it is shown that nucleophiles unable to undergo beta-hydride elimination, such as MeLi, PhLi, or PhMgBr, rapidly reduce Fe(3+) to Fe(2+...

Journal: :Chemical biology & drug design 2012
Matt Gooding Slavica Tudzarova Roberta J Worthington Sarah R Kingsbury Anne-Sophie Rebstock Henry Dube Michela I Simone Cristina Visintin Dimitris Lagos Juan-Manuel Funes Quesada Heike Laman Chris Boshoff Gareth H Williams Kai Stoeber David L Selwood

The small molecule carrier class of biomolecule transporters, modeled on the third helix of the Antennapedia homeodomain, has previously been shown to transport active proteins into cells. Here, we show an improved synthetic route to small molecule carriers, including Molander chemistry using trifluoroborate salts to improve the yield of the Suzuki-Miyaura coupling step for the formation of the...

2014
Mark W. Kryman Gregory A. Schamerhorn Jacqueline E. Hill Brandon D. Calitree Kellie S. Davies Michelle K. Linder Tymish Y. Ohulchanskyy Michael R. Detty

Analogues of Texas red incorporating the heavy chalcogens S, Se, and Te atoms in the xanthylium core were prepared from the addition of aryl Grignard reagents to appropriate chalcogenoxanthone precursors. The xanthones were prepared via directed metalation of amide precursors, addition of dichalcogenide electrophiles, and electrophilic cyclization of the resulting chalcogenides with phosphorus ...

Journal: :Reaction Chemistry and Engineering 2023

Grignard reagent formation in continuously operated magnesium packed-bed reactors can be influenced by finetuning the residence time distribution within packing. By decreasing turning size and increasing...

2015
Sambasivarao Kotha Ajay Kumar Chinnam Mukesh Eknathrao Shirbhate

We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps.

Journal: :Chemical communications 2008
Hirohisa Todo Jun Terao Hideyuki Watanabe Hitoshi Kuniyasu Nobuaki Kambe

The carbomagnesiation of dienes and enynes with sec- and tert-alkyl Grignard reagents has been achieved by using copper salts as catalysts.

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