Secreted frizzled-related proteins (sFRPs) are secreted glycoproteins involved in neoplastic growth. Four hormones synthesized in the heart, namely vessel dilator, atrial natriuretic peptide (ANP), kaliuretic peptide (KP) and long-acting natriuretic peptide (LANP), have anticancer effects both in vitro and in vivo. These heart hormones were evaluated for their ability to inhibit sFRP-3, which i...

OPTIC FLOW IS THE PATTERN of motion present at the eye of a moving observer. Such flow patterns contain information about self-motion, moving objects, and the threedimensional (3D) layout of the environment, and could potentially be exploited to control locomotion. The term was first used by Gibson (1950) to generalize Helmholtz's notion of motion parallax from single objects to the continuous ...

Extrahepatic bile duct carcinoma is one of the most extremely aggressive cancers with poor prognosis after curative resection. Syndecan-1 and E-cadherin are transmembrane glycoproteins, and have important roles in cell-cell adhesion and tumor progression. In this study, we examined 84 surgically resected cases of extrahepatic bile duct adenocarcinoma to clarify clinicopathological significance ...

The dodder plant Cuscuta reflexa Roxb. is an angiospermic leafless parasitic plant belonging to the family Cuscutaceae is abundantly found colonizing certain plant species in the premises of Manas Biosphere Reserve (MBR) and nearby area. Ten (10) angiospermic host plants in total of the above parasite were recognized. Based on the field inspection most of the numbers of patches were recorded in...

BACKGROUND Cyclooxygenase (COX)-2 is overexpressed in several tumor entities and seems to play a key role in carcinogenesis. This makes it a potential target in cancer therapy. MATERIALS AND METHODS Twelve phosphorothioate-modified antisense oligonucleotides (asODNs) against six targets of COX-2 mRNA were transfected to A-549 lung carcinoma cells. COX-2 mRNA and protein levels were determined...

background and purpose: mycotoxins are secondary fungal metabolites with a very high diversity that are produced by some species of aspergillus which frequently leads to contaminate food and agricultural products. recently, elimination of aflatoxin contamination in food and feed has been considered by scientists worldwide. although, the antibacterial and antifungal effects of vitamins as natura...

Expression of the WWOX gene, encompassing the common chromosome fragile site FRA16D, is altered in a large fraction of cancers of various types, including prostate cancer. We have examined expression and biological functions of WWOX in prostate cancer. WWOX mRNA and protein expression were significantly reduced in prostate cancer-derived cells (LNCaP, DU145, and PC-3) compared with noncancer pr...

trehalose is an important disaccharide signal metabolite in plants which is involved in various aspects of plant function such as response to stress, photosynthesis and carbon allocation and partitioning. a mutant of arabidopsis lacking trehalose-6-phosphate synthase activity (tps1) accumulates ascorbate. exogenous ascorbate application ameliorates trehalose induced growth inhibition of wild ty...