نتایج جستجو برای: ascot

تعداد نتایج: 339  

Journal: :Diabetes care 2005
Peter S Sever Neil R Poulter Björn Dahlöf Hans Wedel Rory Collins Gareth Beevers Mark Caulfield Sverre E Kjeldsen Arni Kristinsson Gordon T McInnes Jesper Mehlsen Markku Nieminen Eoin O'Brien Jan Ostergren

OBJECTIVE This study aims to establish the benefits of lowering cholesterol in diabetic patients with well-controlled hypertension and average/below-average cholesterol concentrations, but without established coronary disease. RESEARCH DESIGN AND METHODS In the lipid-lowering arm of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT-LLA), 10,305 hypertensive patients with no history of coro...

2011
K. Shinohara T. Kurki-Suonio D. Spong O. Asunta K. Tani E. Strumberger S. Briguglio T. Koskela G. Vlad

Within the ITPA Topical Group on Energetic Particles, we have investigated the impact that various mechanisms breaking the tokamak axisymmetry can have on the fusion alpha particle confinement in ITER as well as on the wall power loads due to these alphas. In addition to the well-known TF ripple, the 3D effect due to ferromagnetic materials (in ferritic inserts and test blanket modules) and ELM...

2012
Harshal A. Deshmukh Helen M. Colhoun Toby Johnson Paul M. McKeigue D. John Betteridge Paul N. Durrington John H. Fuller Shona Livingstone Valentine Charlton-Menys Andrew Neil Neil Poulter Peter Sever Denis C. Shields Alice V. Stanton Aurobindo Chatterjee Craig Hyde Roberto A. Calle David A. DeMicco Stella Trompet Iris Postmus Ian Ford J. Wouter Jukema Mark Caulfield Graham A. Hitman

We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the observational phase of ASCOT (n = 651), all of whom were prescribed atorvastatin 10 mg. Following genome-wide imputation, we combined data from t...

Journal: :Journal of hypertension 2011
David J Collier Neil R Poulter Björn Dahlöf Peter S Sever Hans Wedel Jan Buch Mark J Caulfield

OBJECTIVES Older patients experience higher rates of cardiovascular disease than younger patients, but studies have suggested that relative risk reductions due to antihypertensive therapy are lower in older than younger patients. The Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) allowed an evaluation of the efficacy and safety of an amlodipine versus an aten...

2015
T. Koskela A. Snicker S. Sipilä A. Salmi T. Johnson C. Marchetto M. Schneider M. Romanelli

T. Koskela1, A. Snicker1,7, S. Sipilä1, A. Salmi2, T. Johnson3, C. Marchetto4, M. Schneider5 M. Romanelli6, H. Weisen8, and JET contributors EUROfusion Consortium, JET, Culham Science Centre, Abingdon, OX14 3DB, UK 1 Aalto University School of Science, Espoo, Finland; 2 VTT Technical Research Centre, Finland; 3 Department of Fusion Plasma Physics, School of Electrical Engineering, KTH Royal Ins...

2015
Norma B. Bulamu Billingsley Kaambwa Julie Ratcliffe

BACKGROUND This paper describes the methods and results of a systematic review to identify instruments used to measure quality of life outcomes in older people. The primary focus of the review was to identify instruments suitable for application with older people within economic evaluations conducted in the aged care sector. METHODS Online databases searched were PubMed, Medline, Scopus, and ...

Journal: :Lancet 2011
Anil Nigam Martin Juneau

1202 www.thelancet.com Vol 378 October 1, 2011 Survival benefi t associated with low-level physical activity 2 Prospective Studies Collaboration. Age-specifi c relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903–13. 3 Sever PS, Dahlöf B, Poulter NR, et al, for the ASCOT investigators...

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