نتایج جستجو برای: aspartate receptor encephalitis

تعداد نتایج: 637185  

2015
KURT-WOLFRAM SÜHS FLORIAN WEGNER THOMAS SKRIPULETZ CORINNA TREBST SAID BEN TAYEB PETER RAAB MARTIN STANGEL

Anti-N-methyl D-aspartate (NMDA) receptor encephalitis is the most common type of encephalitis in the spectrum of autoimmune encephalitis defined by antibodies targeting neuronal surface antigens. In the present study, the clinical spectrum of this disease is presented using instructive cases in correlation with the anti-NMDA receptor antibody titers in the cerebrospinal fluid (CSF) and serum. ...

Journal: :Brain : a journal of neurology 2012
Russell C Dale Vera Merheb Sekhar Pillai Dongwei Wang Laurence Cantrill Tanya K Murphy Hilla Ben-Pazi Sophia Varadkar Tim D Aumann Malcolm K Horne Andrew J Church Thomas Fath Fabienne Brilot

Recent reports of autoantibodies that bind to neuronal surface receptors or synaptic proteins have defined treatable forms of autoimmune encephalitis. Despite these developments, many cases of encephalitis remain unexplained. We have previously described a basal ganglia encephalitis with dominant movement and psychiatric disease, and proposed an autoimmune aetiology. Given the role of dopamine ...

2014
Yuki Hayata Kensuke Hamada Yasuhisa Sakurai Izumi Sugimoto Toru Mannen Yukitoshi Takahashi

BACKGROUND Little is known about the difference between anti-N-methyl-D-aspartate receptor (NMDAR) antibody-positive encephalitis and anti-glutamate receptor (GluR) antibody-positive encephalitis. OBJECTIVES To characterize anti-GluR antibody-positive encephalitis. METHODS We report a 33-year-old man with nonparaneoplastic anti-GluR ∊2, ζ1 and δ2 antibody-positive and anti-NMDAR antibody-ne...

2017
Kenneth E. Remy Jason W. Custer Joshua Cappell Cortney B. Foster Nan A. Garber L. Kyle Walker Liliana Simon Dayanand Bagdure

Purpose Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is being recognized with increasing frequency among children. Given the paucity of evidence to guide the critical care management of these complex patients, we provide a comprehensive review of the literature with pooled analysis of published case reports and case series. Methods We performed a comprehensive literature search usi...

Journal: :Neurology 2022

Objective To assess the safety and efficacy of inebilizumab in patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Background The lack approved therapies for NMDAR encephalitis has led to substantial variability treatment. High-quality data is needed guide treatment optimize long-term outcomes recovering patients. Inebilizumab a humanized anti-CD19 monoclonal antibody that ca...

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