Recently, the Aspergillus terreus terrein gene cluster was identified and selected for development of a new heterologous expression system. The cluster encodes the specific transcription factor TerR that is indispensable for terrein cluster induction. To identify TerR binding sites, different recombinant versions of the TerR DNA-binding domain were analyzed for specific motif recognition. The h...

We examined the in vitro activity of caspofungin, posaconazole, voriconazole, ravuconazole, itraconazole, and amphotericin B against 448 recent clinical mold isolates. The endpoint for reading caspofungin was the minimum effective concentration (MEC). Among the triazoles, posaconazole was most active, inhibiting 95% of isolates at <or=1 microg/ml, followed by ravuconazole (91%), voriconazole (9...

Background: Essential oils (EOs) are recommended by some veterinarians to treat otitis externa in pets, but data about their efficacy in scientific literature are very scant. Methods: Nine commercial EOs, from roman chamomile (Anthemis nobilis L.), star anise (Illicium verum), lavender (Lavandula hybrida), litsea (Litsea cubeba (Lour.) Pers.), basil (Ocimum basilicum L.), oregano (Origanum vulg...

A number of benzoic acid analogues showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. Structure-activity analysis revealed that antifungal activities of benzoic and gallic acids were increased by addition of a methyl, methoxyl or chloro group at position 4 of the aromati...

This study was conducted to estimation of fungal species and aflatoxin B1 in some types Spices Salah Al-deen governorate markets. In this Six Aspergillus were detected which A. flavus, parasiticus, fumigatus, terreus, ochraceus niger 5 genus fungi Fusarium verticillioides, Penicillium, Mucor, Alternariaand Rhizopus isolated on the three media used. The results show presence mycotoxins all sampl...

Moulds constitute the largest group of bacteria, prevailing both in the indoor and outdoor air. Approximately 200 000 species of moulds have been identified so far, where only a small group of around 200 may present a threat to human health. Fungi from Aspergillus species are among the moulds considered to be most pathogenic. They also constitute the group of most pathogenic moulds most frequen...

Itaconic acid was best produced by fungal species than bacterial species. The A. niger and A. terreus were known to be the best species for itaconic acid production among the different fungal species studied. However, there was no comprehensive study on using latest technologies for increasing the productivity at industrial level and it was not properly established. By keeping this in view, the...

The fungitoxic properties of vapours of essential oil extracted from Cinnamon (Cinnamomum zeylanicum Breyn) bark have been investigated against five species of Aspergillus viz. A. flavus Link, A. fumigatus Fresenius, A. nidulans (Eidam) Wingate, A. niger van Tiegham and A. terreus Thom, causing biodeterioration of paper manuscripts in Gorakhpur. The fungitoxicity was determined in vitro as mini...