Objective(s): High-glucose (HG) stress, a mimic of diabetes mellitus (DM) in culture cells, alters expression of a large number of genes including Wnt and NF-κB signaling-related genes; however, the role of Wnt signaling during HG-mediated fibroblast damage and the relationship between Wnt and NF-κB signaling have not been understood. In this study, we aimed to investigate the ffects of Wnt sig...

Blending ultrafine-grained microstructure with other added reinforcement elements that can provide good strength-microstructural integrity is the primary metallurgical target for any developed composite to exhibit its maximum strength at reduced cost and energy in aerospace application. Such nano-reinforced aluminium alloy composites are processed through addition of nano alumina using powder m...

Thin films, consisting of a sol–gel Nb2O5 matrix doped with zeolite Na-X synthesized from fly ash through ultrasonic-assisted double-stage fusion-hydrothermal alkaline activation, were deposited by the spin-coating method. In order to improve optical quality and sensing properties thin zeolites wet milled for 60, 120 540 s prior incorporation in film. The liquid adsorption ability films was tes...

The current mechanism proposed for the processing and activation of the 52 kDa lysosomal aspartic protease cathepsin D (cath-D) is a combination of partial auto-activation generating a 51 kDa pseudo-cath-D, followed by enzyme-assisted maturation involving cysteine and/or aspartic proteases and yielding successively a 48 kDa intermediate and then 34 + 14 kDa cath-D mature species. Here we have i...

Fertilization is triggered by changes in intracellular calcium concentration. In mammals, these transients in ooplasmic calcium concentration take the form of repetitive spikes, so called calcium oscillations (Ca-oscillations). These oscillations are important for relieve of meiotic arrest and to induce all the other events of oocyte activation. Although a surface mediated way of oocyte activat...

Plasma-assisted deposition is a facile, yet sophisticated method to form biocompatible coatings on materials and introduce specific surface interactions. The plasma process provides unique features such as activation, functionalization, assisted polymerization, all of which can be obtained under low power room temperature conditions. further provide with enhanced adhesion stability. Here, it re...

in this study, the adsorption of hexavalent chromium and zinc ions from the solution is investigated by raw red mud and mechanical-chemical activated red mud along with the possibility of selective reclamation of these ions from the solution. the mechanical-chemical activation of red mud was done by employing high-energy milling and subsequent acid treatment with hno3. raw red mud (rrm) and mec...

cotton fibres were subjected to cleaning process and then characterized for maturity. decrystallisation and swelling processes with caustic soda, ethanol, propan-2-ol and trichloroethene on the native fibres were carried out. the effects of these on the strength and moisture regain were investigated. the activation energies of the dyeings were also analysed with durazol scarlet red 4 bas. the r...